Gene Symbol | AMIGO2 |
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Entrez Gene | 347902 |
Alt Symbol | ALI1, AMIGO-2, DEGA |
Species | Human |
Gene Type | protein-coding |
Description | adhesion molecule with Ig-like domain 2 |
Other Description | alivin 1|amphoterin induced gene 2|amphoterin-induced protein 2|differentially expressed in gastric adenocarcinoma|differentially expressed in gastric adenocarcinomas|transmembrane protein AMIGO2 |
Swissprots | Q96CN8 Q4VBP6 Q86SJ2 Q7Z4A0 |
Accessions | CCF77052 EAW57923 EAW57924 Q86SJ2 AB079074 BAC81188 AB080610 BAC81189 AK091761 BAG52413 AK093111 BAG52657 AL833007 CAH56293 AY237005 AAO48946 AY454159 AAR83271 BC014103 AAH14103 BC047595 AAH47595 BC095477 AAH95477 CN397638 XM_005268837 XP_005268894 NM_001143668 NP_001137140 NM_181847 NP_862830 |
Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers. {ECO:0000269|PubMed:15107827}. |
Human AMIGO2 full length protein - ab166332 from Abcam
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AMIGO2 Antibody Blocking Peptide - LS-E20194 from LifeSpan Bioscience
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AMIGO2 Recombinant Protein - H00347902-P01 from Novus Biologicals
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AMIGO2-Antibody-C-term-Blocking-peptide - BP13394b from Abgent, a WuXi AppTec company
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Recombinant Human AMIGO2 Fc Chimera, CF - 2080-AM-050 from R&D Systems
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Amigo2 Blocking Peptide - 33R-2918 from Fitzgerald
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AMIGO2 / ALI1 - H00347902-P01 from Acris Antibodies
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AMIGO2 fusion protein - Ag5200 from Proteintech Group
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AMIGO2 fusion protein - ag5067 from Proteintech Group
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Recombinant Human AMIGO2, His-tagged - AMIGO2-9618H from Creative Biomart
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Recombinant Human AMIGO2, His tagged - AMIGO2-568H from Creative Biomart
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Recombinant Human AMIGO2, His-tagged - AMIGO2-28H from Creative Biomart
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Human AMIGO2 Protein (His Tag) - 13735-H08H-20 from Sino Biological
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Recombinant Human Amphoterin-induced protein 2(AMIGO2) - CSB-YP769765HU CSB-EP769765HU CSB-BP769765HU CSB-MP769765HU from Cusabio
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AMIGO2 / ALI1 (40-398, His-tag) - AR51985PU-N from Acris Antibodies
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AMIGO2 / ALI1 (40-398, His-tag) - AR51985PU-S from Acris Antibodies
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Recombinant Human AMIGO2 Fc Chimera Protein, CF - 2080-AM from R&D Systems
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Amphoterin-induced protein 2, 40-398aa, Human, His tag, Baculovirus - ATGP3230 from ATGen
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Amphoterin-induced protein 2(AMIGO2) , Recombinant Protein - MBS1368385 from MyBioSource
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Recombinant Human AMIGO2 Protein (His tag) - PKSH030569 from Elabscience
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Recombinant Human AMIGO2 Protein, His-tagged - AMIGO2-385H from Creative Biomart
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AMIGO2 Protein - NBP2-14288PEP from Novus Biologicals
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AMIGO2 protein - 80R-4377 from Fitzgerald
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AMIGO2 Peptide, Human - M34GP00557H from Creative Peptides
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Recombinant Human AMIGO2 Protein - NBP2-52230 from Novus Biologicals
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