Gene Symbol | TAF8 |
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Entrez Gene | 129685 |
Alt Symbol | 43, II, TAF, TAFII-43, TAFII43, TBN |
Species | Human |
Gene Type | protein-coding |
Description | TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa |
Other Description | TAF(II)43|TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa|TBP-associated factor 43 kDa|TBP-associated factor 8|TBP-associated factor TAFII43|TBP-associated factor, RNA polymerase II, 43 kD|hTAFII43|protein taube nuss|taube nuss homolog|transcription initiation factor TFIID 43 kDa subunit|transcription initiation factor TFIID subunit 8 |
Swissprots | Q96M52 Q5T0K1 Q7Z7C8 Q8N4R9 |
Accessions | EAX04078 EAX04079 EAX04080 Q7Z7C8 AF086309 AF465841 AAP47094 AK057383 BAB71460 AK303097 BAG64207 AL833401 BC018796 BC033728 BC119678 AAI19679 BC119679 AAI19680 BI828714 XM_005248849 XP_005248906 XM_011514296 XP_011512598 XM_011514297 XP_011512599 NM_138572 NP_612639 |
Function | Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14580349}. Cytoplasm {ECO:0000250}. Note=Localized in the cytoplasm and transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell. {ECO:0000250}. |
Top Pathways | Basal transcription factors |
Human TAF8 full length protein - ab165318 from Abcam
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TAF8 Antibody Blocking Peptide - LS-E2409 from LifeSpan Bioscience
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TAF8 Antibody Blocking Peptide - LS-E27219 from LifeSpan Bioscience
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TAF8 Antibody Blocking Peptide - LS-E18945 from LifeSpan Bioscience
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Recombinant Human TAF8 Protein - H00129685-P01 from Novus Biologicals
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TAF8-Antibody-Center-Blocking-peptide - BP13397c from Abgent, a WuXi AppTec company
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TAF8/TAFII43 blocking peptide - GTX88250-PEP from GeneTex
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POLR2F protein (His tag) - 80R-3780 from Fitzgerald
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POLR2H protein (His tag) - 80R-2776 from Fitzgerald
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POLR2K protein (His tag) - 80R-4027 from Fitzgerald
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TAF8 Peptide - AC21-2040-P from Abcore
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TAF8 / TAFII43 / TBN - H00129685-P01-10 from Acris Antibodies
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TAF8 / TAFII43 / TBN - H00129685-P01-25 from Acris Antibodies
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TAF8 Peptide - 42-253P from ProSci
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TAF8 fusion protein - ag4577 from Proteintech Group
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Biotin-Angiotensin I/II (1-7) - 59203 from NeoScientific
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POLR2E Human - ENPS-680 from NeoScientific
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Recombinant Human Transcription initiation factor TFIID subunit 8(TAF8) - CSB-YP773805HU CSB-EP773805HU CSB-BP773805HU CSB-MP773805HU from Cusabio
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Recombinant Schistocerca gregaria Serine protease inhibitor I/II - CSB-YP524300SXO CSB-EP524300SXO CSB-BP524300SXO CSB-MP524300SXO from Cusabio
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Recombinant Bison bonasus Hemoglobin subunit alpha-I/II - CSB-YP357673BTF CSB-EP357673BTF CSB-BP357673BTF CSB-MP357673BTF from Cusabio
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Recombinant Triticum aestivum EC protein I/II - CSB-YP328998TQN CSB-EP328998TQN CSB-BP328998TQN CSB-MP328998TQN from Cusabio
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TAF8 / TAFII43 / TBN (full length, N-term HIS tag) - TP760679 from Acris Antibodies
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TAF8/TAFII43, Peptide - MBS425856 from MyBioSource
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TAF8 Protein - NBP2-38189PEP from Novus Biologicals
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TAF8 Recombinant Protein Antigen - NBP2-38188PEP from Novus Biologicals
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