Gene Symbol | TAF8 |
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Entrez Gene | 129685 |
Alt Symbol | 43, II, TAF, TAFII-43, TAFII43, TBN |
Species | Human |
Gene Type | protein-coding |
Description | TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa |
Other Description | TAF(II)43|TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa|TBP-associated factor 43 kDa|TBP-associated factor 8|TBP-associated factor TAFII43|TBP-associated factor, RNA polymerase II, 43 kD|hTAFII43|protein taube nuss|taube nuss homolog|transcription initiation factor TFIID 43 kDa subunit|transcription initiation factor TFIID subunit 8 |
Swissprots | Q96M52 Q5T0K1 Q7Z7C8 Q8N4R9 |
Accessions | EAX04078 EAX04079 EAX04080 Q7Z7C8 AF086309 AF465841 AAP47094 AK057383 BAB71460 AK303097 BAG64207 AL833401 BC018796 BC033728 BC119678 AAI19679 BC119679 AAI19680 BI828714 XM_005248849 XP_005248906 XM_011514296 XP_011512598 XM_011514297 XP_011512599 NM_138572 NP_612639 |
Function | Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14580349}. Cytoplasm {ECO:0000250}. Note=Localized in the cytoplasm and transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell. {ECO:0000250}. |
Top Pathways | Basal transcription factors |
TAF II p43 (B-7) - sc-398062 from Santa Cruz Biotechnology
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TAF II p43 (H-271) - sc-368632 from Santa Cruz Biotechnology
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TAF II p43 (P-13) - sc-109442 from Santa Cruz Biotechnology
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Anti-Listeria monocytogenes I/II antibody - ab78729 from Abcam
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Anti-TAF8 antibody - ab77059 from Abcam
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Anti-TAF8 antibody - ab114114 from Abcam
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Anti-TAF8 antibody - ab118730 from Abcam
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Anti-TAF8 Antibody (aa77-89) - LS-C108922 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, APC) - LS-C241514 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, Biotin) - LS-C241515 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, FITC) - LS-C241516 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, AP) - LS-C241513 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, PE) - LS-C241517 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa109-158) - LS-C145775 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa150-178) - LS-C325561 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178, Azide-free, HRP) - LS-C248302 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa260-310) - LS-C289883 from LifeSpan Bioscience
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Anti-TAF8 Antibody (aa151-178) - LS-C157131 from LifeSpan Bioscience
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TAF8 Antibody - NBP2-38189 from Novus Biologicals
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TAF8 Antibody - NBP2-38188 from Novus Biologicals
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TAF8 Antibody - NBP1-81986 from Novus Biologicals
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TAF8 Antibody - H00129685-B01P from Novus Biologicals
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TAF8 Antibody - NBP1-46131 from Novus Biologicals
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TAF8 Antibody - H00129685-D01P from Novus Biologicals
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Anti-TBN antibody produced in mouse - SAB1408305 from Sigma-Aldrich
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