Cdkn1a

Gene Symbol Cdkn1a
Entrez Gene 12575
Alt Symbol CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
Species Mouse
Gene Type protein-coding
Description cyclin-dependent kinase inhibitor 1A (P21)
Other Description CDK-interacting protein 1|cyclin-dependent kinase inhibitor 1|cyclin-dependent kinase inhibitor 1A variant 1|cyclin-dependent kinase inhibitor 1A variant 2|melanoma differentiation-associated protein|p21<WAF1/CIP1>
Swissprots P39689
Accessions AAL57889 AAT73700 AGH67764 AGH67765 EDL22607 EDL22608 EDL22609 P39689 AB017817 BAA82341 AB017818 BAA82342 AK007630 BAB25148 AK089093 BAC40747 AK139306 BAE23949 AK149910 BAE29160 AK170467 BAE41815 AK194916 AK202927 AK210703 BC002043 AAH02043 BY206886 CT010218 CAJ18426 U09507 AAB60456 U24173 AAC52220 NM_001111099 NP_001104569 NM_007669 NP_031695
Function May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20154723}.
Top Pathways HTLV-I infection, MicroRNAs in cancer, Epstein-Barr virus infection, Oxytocin signaling pathway, Proteoglycans in cancer

Anti-p21 antibody [65] - ab99853 from Abcam

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 65

Anti-p21 antibody [HUGO291] - ab107099 from Abcam

Prices $384.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone HUGO291
ab107099 at 1/100 staining p21 in Mouse irradiated skin tissue by Immunohistochemistry.

Anti-p21 antibody - BSA and Azide free - ab80635 from Abcam

Prices $372.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

p21/CIP1/CDKN1A Antibody - NB100-91908 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: p21 Cip1 Antibody [NB100-91908] - Western blot (WB) analysis of p21 Cip1 (G139) Antibody in extracts from Hela cell treated with EGF 200ng/ml 30 minutes

CDKN1A Polyclonal Antibody - bs-0741R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human laryngeal squamous cell carcinoma labeled Anti-P21/CDKN1A Polyclonal Antibody, Unconjugated (bs-0741R) at 1:200, followed by conjugation to the secondary antibody and DAB staining

CDKN1A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0741R-A350 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0741R-A488 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0741R-A555 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0741R-A647 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, Cy3 Conjugated - bs-0741R-Cy3 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, Cy5 Conjugated - bs-0741R-Cy5 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, Cy5.5 Conjugated - bs-0741R-Cy5.5 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, Cy7 Conjugated - bs-0741R-Cy7 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, FITC Conjugated - bs-0741R-FITC from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, Biotin Conjugated - bs-0741R-Biotin from Bioss

Prices $359.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Polyclonal Antibody, HRP Conjugated - bs-0741R-HRP from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-MOUSE P21CIP1 (C-TERM S148) antibody produced in rabbit - SAB1306726 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Mouse p21Cip1 (C-term S148): <B>Cat. No. SAB1306726</B>: Mouse p21Cip1 Antibody (C-term S148) western blot analysis in Mouse NIH-3T3 cell line lysates (35 μg/lane).

ANTI-PHOSPHO-MOUSE P21CIP1(S78) antibody produced in rabbit - SAB1305571 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal

ANTI-PHOSPHO-MOUSE P21CIP1(S125) antibody produced in rabbit - SAB1305570 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal

Phospho-mouse-p21Cip1S78-Antibody - AP3877a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot analysis of Mouse p21Cip1 Antibody (Phospho S78) Phospho-specific Pab (Cat. #AP3877a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Phospho-mouse-p21Cip1S125-Antibody - AP3875a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot analysis of Mouse p21Cip1 Antibody (Phospho S125) Phospho-specific Pab (Cat. #AP3875a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Mouse-p21Cip1-Antibody-C-term-S148 - AP20419b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Mouse p21Cip1 Antibody (C-term S148) (Cat. #AP20419b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Mouse p21Cip1 antibody detected the Mouse p21Cip1 protein (arrow).

p21Cip1 Antibody (Phospho-Ser125) (OAAB16424) - OAAB16424 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

p21Cip1 Antibody (Phospho-Ser78) (OAAB16426) - OAAB16426 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CDKN1A Antibody - C-terminal region (OAAB17945) - OAAB17945 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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