Cdkn1a

Gene Symbol	Cdkn1a
Entrez Gene	12575
Alt Symbol	CAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
Species	Mouse
Gene Type	protein-coding
Description	cyclin-dependent kinase inhibitor 1A (P21)
Other Description	CDK-interacting protein 1|cyclin-dependent kinase inhibitor 1|cyclin-dependent kinase inhibitor 1A variant 1|cyclin-dependent kinase inhibitor 1A variant 2|melanoma differentiation-associated protein|p21<WAF1/CIP1>
Swissprots	P39689
Accessions	AAL57889 AAT73700 AGH67764 AGH67765 EDL22607 EDL22608 EDL22609 P39689 AB017817 BAA82341 AB017818 BAA82342 AK007630 BAB25148 AK089093 BAC40747 AK139306 BAE23949 AK149910 BAE29160 AK170467 BAE41815 AK194916 AK202927 AK210703 BC002043 AAH02043 BY206886 CT010218 CAJ18426 U09507 AAB60456 U24173 AAC52220 NM_001111099 NP_001104569 NM_007669 NP_031695
Function	May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20154723}.
Top Pathways	HTLV-I infection, MicroRNAs in cancer, Epstein-Barr virus infection, Oxytocin signaling pathway, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) - RPE624Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Cyclin-dependent kinase inhibitor 1(Cdkn1a) - CSB-YP005086MO CSB-EP005086MO CSB-BP005086MO CSB-MP005086MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

p21 (1-159) - sc-4078 from Santa Cruz Biotechnology Category Protein Prices $167.00 Sizes 50 µg/ml Species Mouse

p21, WAF1, Recombinant Protein - MBS636745 from MyBioSource Category Protein Prices $375.00 Sizes 50 µl Source Human, Recombinant (E Coli)

Recombinant Mouse CDKN1A Protein - CDKN1A-3220M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Mouse-p21Cip1-Blocking-Peptide-C-term-S148 - BP20419b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Phospho-mouse-p21Cip1S78-Blocking-Peptide - BP3877a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-p21Cip1S125-Blocking-Peptide - BP3875a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Cyclin-dependent kinase inhibitor 1 (Cdkn1a), Recombinant Protein - MBS950420 from MyBioSource Category Protein Prices $900.00, $900.00, $1,125.00, $1,125.00, $1,330.00, $1,330.00, $1,785.00, $1,785.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Search more