PSIP1

Gene Symbol	PSIP1
Entrez Gene	11168
Alt Symbol	DFS70, LEDGF, PAIP, PSIP2, p52, p75
Species	Human
Gene Type	protein-coding
Description	PC4 and SFRS1 interacting protein 1
Other Description	CLL-associated antigen KW-7|DFS 70|PC4 and SFRS1-interacting protein|dense fine speckles 70 kDa protein|lens epithelium-derived growth factor|transcriptional coactivator p52/p75|transcriptional coactivator p75/p52
Swissprots	Q9NZI3 O95368 Q9UER6 O75475 Q6P391 D3DRI9 Q86YB9 O00256
Accessions	AAF25870 AAF25871 CCQ43795 EAW58675 EAW58676 EAW58677 EAW58678 EAW58679 O75475 AF063020 AAC25167 AF098482 AAC97945 AF098483 AAC97946 AF432220 AAL99926 AK096405 BC013160 BC022971 AAH22971 BC033817 AAH33817 BC040032 BC044568 AAH44568 BC064135 AAH64135 BQ186453 BX649155 DA117094 U94319 AAB52589 XM_005251358 XP_005251415 XM_011517697 XP_011515999 XM_011517698 XP_011516000 XM_011517699 XP_011516001 XM_011517700 XP_011516002 NM_001128217 NP_001121689 NM_021144 NP_066967 NM_033222 NP_150091
Function	Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. {ECO:0000269|PubMed:15642333}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15642333, ECO:0000269|PubMed:9885563}. Note=Remains chromatin-associated throughout the cell cycle.
Tissue Specificity	Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. {ECO:0000269|PubMed:15642333, ECO:0000269|PubMed:9822615}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSIP1 / LEDGF ELISA Kit (Sandwich ELISA) - LS-F12436 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

PC4 and SFRS1 interacting protein 1 (PSIP1), Human, ELISA Kit - CSB-E17297h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

PC4 and SFRS1-interacting protein, PSIP1, Human, ELISA Kit - E15031h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 78-5000 pg/mL

Lens Epithelium Derived Growth Factor (LEDGF), Human, CLIA Kit - SCG671Hu from ARP American Research Products Category CLIA Kit Prices $783.00 Sizes 96 t Sensitivity 0.124ng/mL Range 0.312-20ng/mL

PC4 and SFRS1 interacting protein 1, ELISA Kit - MBS706164 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PSIP1 is typically less than 11.72 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 46.88 pg/ml -3000 pg/ml.

Human PC4 and SFRS1 interacting protein 1 (PSIP1) ELISA kit - CSB-E17297h from Cusabio Category ELISA Kit Sensitivity 11.72 pg/ml Range 46.88 pg/ml-3000 pg/ml

Rat PSIP1 / LEDGF ELISA Kit (Custom ELISA) - LS-F17682 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Mouse PSIP1 / LEDGF ELISA Kit (Custom ELISA) - LS-F17683 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Chicken PSIP1 / LEDGF ELISA Kit (Custom ELISA) - LS-F17681 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Bovine PSIP1 / LEDGF ELISA Kit (Custom ELISA) - LS-F17680 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

PC4 and SFRS1-interacting protein, ELISA Kit - MBS288472 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.31 ng/ml -20.0 ng/ml.

Lens epithelium-derived growth factor, ELISA Kit - MBS288199 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78 ng/ml -50.0 ng/ml.

PC4 and SFRS1-interacting protein, ELISA Kit - MBS288345 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.15 ng/ml -10.0 ng/ml.

Custom Human LEDGF ELISA - ELH-LEDGF from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

PC4 and SFRS1-interacting protein, ELISA Kit - MBS288483 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.15 ng/ml -10.0 ng/ml.

Lens Epithelium Derived Growth Factor (LEDGF), CLIA Kit - MBS2000661 from MyBioSource Category CLIA Kit Prices $470.00, $695.00, $960.00, $4,005.00, $7,215.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 0.071ng/mL Range 0.014-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 3.33ng/mL, 1.11ng/mL, 0.37ng/mL, 0.123ng/mL, 0.041ng/mL, 0.014ng/mL

Lens Epithelium Derived Growth Factor (LEDGF), CLIA Kit - MBS2001242 from MyBioSource Category CLIA Kit Prices $450.00, $660.00, $915.00, $3,805.00, $6,855.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL Range 0.014-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 3.33ng/mL, 1.11ng/mL, 0.37ng/mL, 0.123ng/mL, 0.041ng/mL, 0.014ng/mL

Lens Epithelium Derived Growth Factor (LEDGF), CLIA Kit - MBS2000516 from MyBioSource Category CLIA Kit Prices $440.00, $645.00, $890.00, $3,705.00, $6,680.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL Range 0.027-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 6.67ng/mL, 2.22ng/mL, 0.74ng/mL, 0.247ng/mL, 0.082ng/mL, 0.027ng/mL

Human LEDGF ELISA Kit - orb319986 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 assays, 192 assays, 480 assays

Human LEDGF ELISA - RAB1559 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

PSIP1 - EKH3456 from Nordic BioSite Sensitivity 46.9pg/ml Range 78-5000pg/ml

PSIP1 ELISA Kit (Human) (OKEH02451) - OKEH02451 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 23 pg/mL Range 78 - 5,000 pg/mL

Custom Human LEDGF ELISA - ELH-LEDGF-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human PSIP1 ELISA Kit - E028384 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human PSIP1 is typically less than 11.72 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

Human PC4 and SFRS1-interacting protein ELISA Kit - EK3586 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 23pg/ml Range 78-5000 pg/mL

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