PSIP1

Gene Symbol	PSIP1
Entrez Gene	11168
Alt Symbol	DFS70, LEDGF, PAIP, PSIP2, p52, p75
Species	Human
Gene Type	protein-coding
Description	PC4 and SFRS1 interacting protein 1
Other Description	CLL-associated antigen KW-7|DFS 70|PC4 and SFRS1-interacting protein|dense fine speckles 70 kDa protein|lens epithelium-derived growth factor|transcriptional coactivator p52/p75|transcriptional coactivator p75/p52
Swissprots	Q9NZI3 O95368 Q9UER6 O75475 Q6P391 D3DRI9 Q86YB9 O00256
Accessions	AAF25870 AAF25871 CCQ43795 EAW58675 EAW58676 EAW58677 EAW58678 EAW58679 O75475 AF063020 AAC25167 AF098482 AAC97945 AF098483 AAC97946 AF432220 AAL99926 AK096405 BC013160 BC022971 AAH22971 BC033817 AAH33817 BC040032 BC044568 AAH44568 BC064135 AAH64135 BQ186453 BX649155 DA117094 U94319 AAB52589 XM_005251358 XP_005251415 XM_011517697 XP_011515999 XM_011517698 XP_011516000 XM_011517699 XP_011516001 XM_011517700 XP_011516002 NM_001128217 NP_001121689 NM_021144 NP_066967 NM_033222 NP_150091
Function	Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. {ECO:0000269|PubMed:15642333}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15642333, ECO:0000269|PubMed:9885563}. Note=Remains chromatin-associated throughout the cell cycle.
Tissue Specificity	Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. {ECO:0000269|PubMed:15642333, ECO:0000269|PubMed:9822615}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSIP1 full length protein - ab82128 from Abcam Category Protein Source E. coli Species Human

Human PSIP1 full length protein - ab82126 from Abcam Category Protein Source E. coli Species Human

Human PSIP1 protein fragment - ab82129 from Abcam Category Protein Source E. coli Species Human

PSIP1 / LEDGF Antibody Blocking Peptide - LS-E12373 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSIP1 / LEDGF Antibody Blocking Peptide - LS-E12313 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSIP1 / LEDGF Antibody Blocking Peptide - LS-E12314 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human LEDGF Protein - H00011168-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human LEDGF Protein - NBP2-23461 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

PSIP2-Antibody-Center-Blocking-peptide - BP11547c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PSIP2-Antibody-C-term-Blocking-Peptide - BP7857b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human LEDGF, CF - 3468-LE-050 from R&D Systems Category Protein Source E. coli-derived, Met1-Asn530

Recombinant Human LEDGF p52, CF - 6044-LE-050 from R&D Systems Category Protein Source E. coli-derived, Met1-Gln333

Human PSIP1 protein - orb244467 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

PSIP1 protein (His tag) - 80-1381 from Fitzgerald Category Protein Prices $125.00, $795.00 Sizes 100 µg, 1 mg

PSIP1 - H00011168-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PSIP1 - H00011168-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PSIP1 fusion protein - ag21886 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human PC4 And SFRS1 Interacting Protein 1 - PSIP1-1078H from Creative Biomart Category Protein Source E.coli .

Recombinant Human PSIP1, 322-530aa - PSIP1-1079H from Creative Biomart Category Protein Source E.coli .

Recombinant Human PSIP1, His-tagged - PSIP1-29365TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PSIP1, His-tagged - PSIP1-31001TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PSIP1, His-tagged - PSIP1-31222TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PSIP1, His-tagged - PSIP1-8485H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PSIP1 - PSIP1-734H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human PSIP1 - PSIP1-789H from Creative Biomart Category Protein Source E. coli Species Human

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