HTR6

Gene Symbol HTR6
Entrez Gene 3362
Alt Symbol 5-HT6, 5-HT6R
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Other Description 5-hydroxytryptamine receptor 6|serotonin receptor 6
Swissprots P50406 Q5TGZ1 Q13640
Accessions EAW94896 P50406 AB209129 BAD92366 AF007141 AY429105 AAR07900 BC074995 AAH74995 BC074996 AAH74996 L41147 AAA92622 Z49119 CAA88929 NM_000871 NP_000862
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611). {ECO:0000250|UniProtKB:P31388, ECO:0000250|UniProtKB:Q9R1C8, ECO:0000269|PubMed:23027611}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in several human brain regions, most prominently in the caudate nucleus.
Top Pathways Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction

SR-6 CRISPR/Cas9 KO Plasmid (h) - sc-402874 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 HDR Plasmid (h) - sc-402874-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 Double Nickase Plasmid (h) - sc-402874-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 Double Nickase Plasmid (h2) - sc-402874-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 CRISPR Activation Plasmid (h) - sc-402874-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 CRISPR Activation Plasmid (h2) - sc-402874-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 Lentiviral Activation Particles (h) - sc-402874-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 Lentiviral Activation Particles (h2) - sc-402874-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-6 siRNA (h) - sc-42244 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-6 shRNA Plasmid (h) - sc-42244-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-6 shRNA (h) Lentiviral Particles - sc-42244-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5-HT6 RNAi - H00003362-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10400 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1107 from Sigma-Aldrich

Category ZFN Kit
Prices $6,000.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01059 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01059

HTR6 siRNA (Human) - CRH2292 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTR6 - MBS8227650 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HTR6 (NM_000871.1) - SHH316017 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HTR6(NM_000871.1) - SHH136235 from Creative biogene

Category siRNA
Species Reactivities Human

Human HTR6 siRNA - orb262794 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTR6 shRNA Plasmid (Human) - CHH2292 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTR6 miRNA 3'UTR clone - MiUTR1H-04758 from Creative biogene

Species Reactivities Human
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