SENP2

Gene Symbol SENP2
Entrez Gene 59343
Alt Symbol AXAM2, SMT3IP2
Species Human
Gene Type protein-coding
Description SUMO1/sentrin/SMT3 specific peptidase 2
Other Description SMT3-specific isopeptidase 2|SUMO1/sentrin/SMT3 specific protease 2|sentrin-specific protease 2|sentrin/SUMO-specific protease SENP2
Swissprots Q96SR2 Q8IW97 Q9HC62 B4DQ42 Q9P2L5
Accessions EAW78214 EAW78215 EAW78216 EAW78217 Q9HC62 AF151697 AAG15309 AK027599 BAB55222 AK074357 AK296744 BAG59328 AK296772 BAG59351 AK298628 BAG60804 AK304402 BAG65236 AL834380 CAD39043 BC018020 BC040609 AAH40609 XM_005247690 XP_005247747 XM_005247691 XP_005247748 NM_021627 NP_067640
Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. {ECO:0000269|PubMed:11896061, ECO:0000269|PubMed:12192048, ECO:0000269|PubMed:21965678}.
Subcellular Location Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Top Pathways Wnt signaling pathway, RNA transport

SENP2 (H-300) - sc-67075 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SENP2 (H-300): sc-67075. Western blot analysis of SENP2 expression in mouse liver tissue extract.

SENP2 (N-14) - sc-46637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SENP2 (S-18) - sc-46638 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SENP2 antibody - ab58418 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SENP2 antibody (ab58418) at 1/500 dilutionLane 1 : MDA-MB-435 cell extractLane 2 : MDA-MB-435 cell extract with immunizing peptide

Anti-SENP2 antibody - ab3660 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab3660 at a 1/100 dilution staining approximately 68 kDa band of SENP2 in Jurkat cell lysate by Western blot (ECL).

Anti-SENP2 antibody - ab96865 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SENP2 antibody (ab96865) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : MOLT-4 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-SENP2 antibody - ab109590 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SENP2 antibody (ab109590) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-SENP2 antibody - ab135134 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-SENP2 antibody (ab135134) at 1/1000 dilutionLane 1 : MDA-MB231 total cell extractLane 2 : Mouse kidney total cell extract

Anti-SENP2 antibody [1H2] - ab131637 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H2
Immunofluorescent analysis of COS7 cells transiently transfected with pCMV6-ENTRY SENP2 labelling SENP2 with ab131637 at 1/100 dilution.

Anti-SENP2 antibody [EPR4356(2)] - ab124724 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4356(2)
All lanes : Anti-SENP2 antibody [EPR4356(2)] (ab124724) at 1/10000 dilutionLane 1 : MDA-MB-435 cell lysateLane 2 : NIH:OVCAR-3 cell lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SENP2 antibody - C-terminal - ab135757 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SENP2 antibody - C-terminal (ab135757) at 1/100 dilution + Mouse heart tissue lysate at 12.5 µg

Anti-SENP2 Antibody (aa139-523, clone 1B8) - LS-C337771 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B8
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-SENP2 Antibody (aa16-32) - LS-C147886 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-SENP2 Antibody (aa481-530) - LS-C118613 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from MDA-MB-435 cells, using SENP2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SENP2 Antibody (aa503-552) - LS-C116689 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SENP2 antibody LS-C116689 Western blot of COLO205 cell lysate.

Anti-SENP2 Antibody - LS-C793 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of SENP2 in 15 ugs of Jurkat cell lysate using antibody at 1:1000.

Anti-SENP2 Antibody (aa502-533) - LS-C98783 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-SENP2 Antibody (Internal, clone EPR4356(2)) IHC-plus™ - LS-B6656 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4356(2)
Anti-SENP2 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6656 dilution 1:50.

Anti-SENP2 Antibody (C-Terminus, APC) - LS-C245745 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SENP2 Antibody (aa139-523, clone 3E7) - LS-C336931 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E7
IHC of paraffin-embedded Human pancreas tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-SENP2 Antibody (clone 1D7) - LS-C175135 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D7
IHC of paraffin-embedded Human liver tissue using anti-SENP2 mouse monoclonal antibody.

Anti-SENP2 Antibody (aa139-523, clone 3B12) - LS-C336929 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B12
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SENP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-SENP2 Antibody (clone 3D3) - LS-C175134 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D3
IHC of paraffin-embedded Human Kidney tissue using anti-SENP2 mouse monoclonal antibody.

Anti-SENP2 Antibody (clone 6F1) - LS-C175138 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6F1
IHC of paraffin-embedded Human Kidney tissue using anti-SENP2 mouse monoclonal antibody.

Anti-SENP2 Antibody (clone 1H2) - LS-C173992 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H2
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SENP2 mouse monoclonal antibody.
Search more