Gene Symbol | SENP2 |
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Entrez Gene | 59343 |
Alt Symbol | AXAM2, SMT3IP2 |
Species | Human |
Gene Type | protein-coding |
Description | SUMO1/sentrin/SMT3 specific peptidase 2 |
Other Description | SMT3-specific isopeptidase 2|SUMO1/sentrin/SMT3 specific protease 2|sentrin-specific protease 2|sentrin/SUMO-specific protease SENP2 |
Swissprots | Q96SR2 Q8IW97 Q9HC62 B4DQ42 Q9P2L5 |
Accessions | EAW78214 EAW78215 EAW78216 EAW78217 Q9HC62 AF151697 AAG15309 AK027599 BAB55222 AK074357 AK296744 BAG59328 AK296772 BAG59351 AK298628 BAG60804 AK304402 BAG65236 AL834380 CAD39043 BC018020 BC040609 AAH40609 XM_005247690 XP_005247747 XM_005247691 XP_005247748 NM_021627 NP_067640 |
Function | Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. {ECO:0000269|PubMed:11896061, ECO:0000269|PubMed:12192048, ECO:0000269|PubMed:21965678}. |
Subcellular Location | Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus. |
Top Pathways | Wnt signaling pathway, RNA transport |
Human-SENP2-cDNA-Clone - DC07370 from Abgent, a WuXi AppTec company
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SENP2 cDNA (ANA11190) - ANA11190 from Aviva Systems Biology
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SENP2 cDNA (ANA11308) - ANA11308 from Aviva Systems Biology
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SENP2 cDNA (ANA11309) - ANA11309 from Aviva Systems Biology
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SENP2 - MBS1277993 from MyBioSource
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Human SENP2 cDNA clone(NM_021627.2) - CDFG001593 from Creative Biomart
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Human SENP2 cDNA clone(NM_021627.2) - CDFG001595 from Creative Biomart
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Human SENP2 ORF Clone(NM_021627.2) - CDCR306974 from Creative Biomart
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Human SENP2 ORF Clone(NM_021627.2) - CDCR306975 from Creative Biomart
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Human SENP2 ORF Clone(NM_021627.2) - CDCL174956 from Creative Biomart
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Human SENP2 ORF Clone(NM_021627.2) - CDCL174957 from Creative Biomart
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human SENP2 ORF clone - CDCH078384 from Creative Biomart
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human SENP2 ORF clone - CDCH078385 from Creative Biomart
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human SENP2 ORF clone - CDCH078386 from Creative Biomart
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human SENP2 ORF clone - CDCH078387 from Creative Biomart
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Human SENP2 Gene cDNA clone plasmid - HG15204-G from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15204-ACG from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15204-NY from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15204-NH from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15204-NF from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15204-ACR from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15204-ANR from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15204-ANG from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15204-CH from Sino Biological
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Human SENP2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15204-CF from Sino Biological
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