SENP2

Gene Symbol	SENP2
Entrez Gene	59343
Alt Symbol	AXAM2, SMT3IP2
Species	Human
Gene Type	protein-coding
Description	SUMO1/sentrin/SMT3 specific peptidase 2
Other Description	SMT3-specific isopeptidase 2|SUMO1/sentrin/SMT3 specific protease 2|sentrin-specific protease 2|sentrin/SUMO-specific protease SENP2
Swissprots	Q96SR2 Q8IW97 Q9HC62 B4DQ42 Q9P2L5
Accessions	EAW78214 EAW78215 EAW78216 EAW78217 Q9HC62 AF151697 AAG15309 AK027599 BAB55222 AK074357 AK296744 BAG59328 AK296772 BAG59351 AK298628 BAG60804 AK304402 BAG65236 AL834380 CAD39043 BC018020 BC040609 AAH40609 XM_005247690 XP_005247747 XM_005247691 XP_005247748 NM_021627 NP_067640
Function	Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. {ECO:0000269|PubMed:11896061, ECO:0000269|PubMed:12192048, ECO:0000269|PubMed:21965678}.
Subcellular Location	Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Top Pathways	Wnt signaling pathway, RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human SENP2 protein fragment - ab188720 from Abcam Category Protein Prices $232.00 Sizes 50 µg Source E. coli Species Human

Human SENP2 protein fragment - ab92035 from Abcam Category Protein Source E. coli Species Human

Human SENP2 protein fragment - ab199592 from Abcam Category Protein Source E. coli Species Human

Mouse SENP2 protein fragment - ab108560 from Abcam Category Protein Source E. coli Species Mouse

SENP2-Antibody-C-term-Blocking-Peptide - BP1233a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SENP2-Antibody-C-term-Blocking-Peptide - BP1232c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SENP2-Antibody-N-term-Blocking-Peptide - BP1232a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human His6-SENP2 Catalytic Domain, CF - E-710-050 from R&D Systems Category Protein Source E. coli-derived, Contains an N-terminal Gly-Ser-Ser and 6-His tag

Human SENP2 protein - orb180409 from Biorbyt Category Protein Prices $179.00, $289.00, $791.00, $1,207.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

SENP2 fusion protein - ag4664 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human SENP2, His-tagged - SENP2-29695TH from Creative Biomart Category Protein Source E. Coli Species Human

Recombinant Human SENP2, GST-tagged - SENP2-687H from Creative Biomart Category Protein Source E. coli.

Recombinant Human SENP2, His-tagged - SENP2-689H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SENP2, His-tagged - SENP2-181H from Creative Biomart Category Protein Source E. coli Species Human

SENP2 Blocking Peptide - CBP2745 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

SENP2 (L512) Peptide - BS1470P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Sentrin-specific protease 2(SENP2) - CSB-YP888026HU CSB-EP888026HU CSB-BP888026HU CSB-MP888026HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human His6-SENP2 Catalytic Domain Protein, CF - E-710 from R&D Systems Category Protein Prices $109.00 Sizes 50 µg Source E. coli -derived Contains an N-terminal Gly-Ser-Ser and 6-His tag Species Human

hDUSP8-S471-haha-antibody-Center-S497-Blocking-Peptide - BP1234 from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Sentrin-specific protease 2 Recombinant Protein - 92-222 from ProSci Category Protein Prices $225.00 Sizes 50 µg Source E. coli Species Human

SENP2, Recombinant Protein - MBS8249755 from MyBioSource Category Protein Prices $120.00, $190.00, $870.00 Sizes 10 µg, 50 µg, 500 µg Source E Coli Species Human

Sentrin-specific protease 2 (SENP2), Recombinant Protein - MBS1442241 from MyBioSource Category Protein Prices $1,390.00, $1,390.00, $1,610.00, $1,610.00, $2,320.00, $2,320.00, $2,765.00, $2,765.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human His6-SENP2 Catalytic Domain Protein, CF - E-710 from Novus Biologicals Category Protein Prices $109.00 Sizes 50 µg Species Human

Recombinant Human Sentrin-Specific Protease 2,SENP2 - AP75909 from Signalway Antibody Category Protein Prices $179.00, $259.00, $969.00, $1,459.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source E. coli Species Human

Human SENP2 protein - orb392445 from Biorbyt Category Protein Species Human

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