Gene Symbol | SIN3B |
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Entrez Gene | 23309 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | SIN3 transcription regulator family member B |
Other Description | SIN3 homolog B, transcriptional regulator|SIN3 transcription regulator homolog B|histone deacetylase complex subunit Sin3b|paired amphipathic helix protein Sin3b|transcriptional corepressor Sin3b |
Swissprots | Q8TB34 Q9BSC8 Q6P4B8 O75182 Q2NL91 Q68GC2 |
Accessions | EAW84564 EAW84565 O75182 AB014600 BAA31675 AK001633 AK295618 BAH12128 AK311023 AY706204 AAU01916 BC005113 AAH05113 BC025026 AAH25026 BC063531 AAH63531 BC110821 AAI10822 BC172412 AAI72412 DB504745 DC332740 HY055983 XM_006722704 XP_006722767 NM_001297595 NP_001284524 NM_001297597 NP_001284526 NM_015260 NP_056075 |
Function | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00810}. |
Human Sin3b full length protein - ab161600 from Abcam
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Human Sin3b protein fragment - ab161601 from Abcam
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SIN3B Antibody Blocking Peptide - LS-E18259 from LifeSpan Bioscience
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SIN3B Antibody Blocking Peptide - LS-E18260 from LifeSpan Bioscience
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SIN3B Antibody Blocking Peptide - LS-E13260 from LifeSpan Bioscience
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Recombinant Human SIN3B Protein - H00023309-P01 from Novus Biologicals
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Recombinant Human SIN3B Protein - H00023309-Q01 from Novus Biologicals
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SIN3B Peptide - orb224284 from Biorbyt
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SIN3B Blocking Peptide - 33R-6663 from Fitzgerald
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SIN3B Blocking Peptide - 33R-6730 from Fitzgerald
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Sin3b Blocking Peptide - 33R-5419 from Fitzgerald
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SIN3B Blocking Peptide - 33R-5540 from Fitzgerald
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SIN3B - H00023309-P01-10 from Acris Antibodies
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SIN3B - H00023309-P01-25 from Acris Antibodies
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SIN3B - H00023309-Q01-10 from Acris Antibodies
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SIN3B - H00023309-Q01-25 from Acris Antibodies
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SIN3B Blocking Peptide - CBP3398 from Cohesion Biosciences
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SIN3B Peptide - BS5930P from Bioworld Technology
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Recombinant Human Paired amphipathic helix protein Sin3b(SIN3B) ,partial - CSB-YP021328HU CSB-EP021328HU CSB-BP021328HU CSB-MP021328HU from Cusabio
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Paired amphipathic helix protein Sin3b (SIN3B), partial, Recombinant Protein - MBS1001605 from MyBioSource
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SIN3B Recombinant Protein Antigen - NBP2-13309PEP from Novus Biologicals
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SIN3B Blocking Peptide - abx162260 from Abbexa
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SIN3B fusion protein - Ag26798 from Proteintech Group
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