SIN3B

Gene Symbol	SIN3B
Entrez Gene	23309
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	SIN3 transcription regulator family member B
Other Description	SIN3 homolog B, transcriptional regulator\|SIN3 transcription regulator homolog B\|histone deacetylase complex subunit Sin3b\|paired amphipathic helix protein Sin3b\|transcriptional corepressor Sin3b
Swissprots	Q8TB34 Q9BSC8 Q6P4B8 O75182 Q2NL91 Q68GC2
Accessions	EAW84564 EAW84565 O75182 AB014600 BAA31675 AK001633 AK295618 BAH12128 AK311023 AY706204 AAU01916 BC005113 AAH05113 BC025026 AAH25026 BC063531 AAH63531 BC110821 AAI10822 BC172412 AAI72412 DB504745 DC332740 HY055983 XM_006722704 XP_006722767 NM_001297595 NP_001284524 NM_001297597 NP_001284526 NM_015260 NP_056075
Function	Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00810}.

mSin3B (AK-12) - sc-768 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

mSin3B (AK-12): sc-768. Western blot analysis of mSin3B expression in HeLa whole cell lysate.

mSin3B (A-20) - sc-996 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

mSin3B (A-20): sc-996. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tumor showing nuclear staining.

mSin3B (H-4) - sc-13145 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

mSin3B (H-4): sc-13145. Western blot analysis of mSin3B expression in HeLa (A) whole cell lysate and HeLa (B) and K-562 (C) nuclear extracts.

mSin3B (H-5) - sc-55516 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

mSin3B (H-5): sc-55516. Western blot analysis of mSin3B expression in HeLa (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

Anti-Sin3b antibody - ab101841 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Sin3b antibody (ab101841) at 1/500 dilution + HCT116 whole cell lysate at 30 µg

Anti-Sin3b antibody - ab101843 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Sin3b antibody (ab101843) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

Anti-Sin3b antibody - ab196668 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Sin3b antibody (ab196668) at 1/500 dilutionLane 1 : A549 cell extractLane 2 : A549 cell extract with immunizing peptide

Anti-Sin3b antibody - ab76231 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Sin3b antibody (ab76231) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Sin3b antibody - ab85192 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Sin3b antibody (ab85192) at 1 µg/ml (in 5% skim milk / PBS buffer) + HCT15 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Sin3b antibody - ab68257 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-Sin3b antibody (ab68257) at 1/500 dilutionLane 1 : Sin3b transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilutionObserved band size : 40 kDa (why is the actual band size different from the predicted?)

Anti-SIN3B Antibody (aa220-269) - LS-C30498 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SIN3B Antibody (aa260-305) - LS-C313952 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SIN3B Antibody (aa614-663) - LS-C81578 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.

Anti-SIN3B Antibody (aa900-949) - LS-C102365 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

SIN3B antibody LS-C102365 Western blot of HCT15 cell lysate.

Anti-SIN3B Antibody (aa221-270) - LS-C199574 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence of HeLa cells, using SIN3B Antibody. The sample on the right was incubated with synthetic peptide.

SIN3B Antibody - NBP2-20367 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: SIN3B Antibody [NBP2-20367] - Sample (30 ug of whole cell lysate) A: HCT116 5% SDS PAGE diluted at 1:500

SIN3B Antibody - NBP1-79381 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: SIN3B Antibody [NBP1-79381] - HCT15 cell lysate, concentration 0.2-1 ug/ml.

SIN3B Antibody - NBP2-20368 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: SIN3B Antibody [NBP2-20368] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 5% SDS PAGE gel, diluted at 1:500.

SIN3B Antibody - H00023309-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: SIN3B Antibody [H00023309-B01] - analysis of SIN3B expression in transfected 293T cell line by SIN3B MaxPab polyclonal antibody (B01). Lane 1: SIN3B transfected lysate (39.50 KDa). Lane 2: Non-transfected lysate.

SIN3B Antibody - H00023309-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: SIN3B Antibody [H00023309-B01P] - Analysis of SIN3B expression in transfected 293T cell line by SIN3B polyclonal antibody. Lane 1: SIN3B transfected lysate(38.83 KDa). Lane 2: Non-transfected lysate.

SIN3B Antibody (2C11) - H00023309-M02 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2C11

Sandwich ELISA: SIN3B Antibody (2C11) [H00023309-M02] - Detection limit for recombinant GST tagged SIN3B is 3 ng/ml as a capture antibody.

Sin3b Polyclonal Antibody - bs-4215R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Rabbit Anti-mSin3A Polyclonal Antibody - bs-4230R from Bioss

Prices	$245.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SIN3B antibody produced in mouse - SAB1407197 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-SIN3B: <B>Cat. No. SAB1407197</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~38.8 kDa using SIN3B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-SIN3B antibody produced in rabbit - HPA050329 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-SIN3B:<B>Cat. No. HPA050329</B>: Immunohistochemical staining of human testis shows moderate nuclear positivity in cells in seminiferus ducts.

Search more