PARVB

Gene Symbol PARVB
Entrez Gene 29780
Alt Symbol CGI-56
Species Human
Gene Type protein-coding
Description parvin, beta
Other Description affixin|beta-parvin
Swissprots Q96PN1 Q86X93 Q5TGJ5 B2R9X6 Q9NSP7 Q9UGT3 B0QYN1 Q9Y3L7 Q9HBI1 B0QYM8 Q9Y3L6 Q9Y368
Accessions EAW73328 EAW73329 EAW73330 EAW73331 Q9HBI1 AB048276 BAB62077 AF151814 AAD34051 AF237769 AAG27171 AF303887 AAL08219 AK308443 AK309987 AK313957 BAG36673 AL159142 CAB76900 BC017461 BC039811 BC046103 AAH46103 BG743702 BP339885 CA308417 CB044150 XM_005261596 XP_005261653 NM_001003828 NP_001003828 NM_001243385 NP_001230314 NM_001243386 NP_001230315 NM_013327 NP_037459
Function Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration. {ECO:0000269|PubMed:11402068, ECO:0000269|PubMed:15005707, ECO:0000269|PubMed:15159419, ECO:0000269|PubMed:15284246, ECO:0000269|PubMed:18325335}.
Subcellular Location Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril, sarcomere, Z line. Note=Constituent of focal adhesions. Detected at the tips of the leading edge of cells. Colocalizes with F-actin at the tips of lamellipodia.
Tissue Specificity Expressed predominantly in heart and skeletal muscle. {ECO:0000269|PubMed:11402068, ECO:0000269|PubMed:11722847}.
Top Pathways Focal adhesion

β-parvin (G-15) - sc-50774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

β-parvin (P-18) - sc-50775 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
β-parvin (P-18): sc-50775. Western blot analysis of β-parvin expression in mouse skeletal muscle tissue extract.

β-parvin (H-45) - sc-134832 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
β-parvin (H-45): sc-134832. Western blot analysis of β-parvin expression in mouse liver (A) and mouse skeletal muscle (B) tissue extracts.

Anti-PARVB antibody - ab80691 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PARVB antibody (ab80691) at 1 µg/ml + transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PARVB antibody - ab57085 from Abcam

Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57085 PARVB antibody at 1ug/ml.

Anti-PARVB antibody [1B7] - ab140384 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B7
All lanes : Anti-PARVB antibody [1B7] (ab140384) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY PARVB cDNALysates/proteins at 5 µg per lane.

Anti-PARVB antibody [EPR11109(B)] - ab154840 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11109(B)
All lanes : Anti-PARVB antibody [EPR11109(B)] (ab154840) at 1/1000 dilutionLane 1 : Human fetal heart lysateLane 2 : HeLa lysateLysates/proteins at 10 µg per lane.

Anti-PARVB Antibody (aa74-123) - LS-C80788 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PARVB Antibody (C-Terminus) - LS-C80789 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PARVB Antibody (clone 2B4) - LS-C337937 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PARVB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PARVB.

Anti-PARVB Antibody (clone 1B9) - LS-C337939 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B9
IHC of paraffin-embedded Human liver tissue using anti-PARVB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-PARVB Antibody (clone 2H1) - LS-C174470 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H1
IHC of paraffin-embedded Human pancreas tissue using anti-PARVB mouse monoclonal antibody.

Anti-PARVB Antibody (clone 2H9) - LS-C337951 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H9
IHC of paraffin-embedded Human pancreas tissue using anti-PARVB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-PARVB Antibody (clone 3G1) - LS-C337952 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3G1
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PARVB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-PARVB Antibody (clone 1B7) - LS-C174477 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B7
IHC of paraffin-embedded Human endometrium tissue using anti-PARVB mouse monoclonal antibody.

PARVB Antibody - NBP1-59135 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PARVB Antibody - NBP1-59129 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PARVB Antibody [NBP1-59129] - Titration: 0.2-1 ug/ml, Positive Control: Transfected 293T.

PARVB Antibody (4A11) - H00029780-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A11
Western Blot: PARVB Antibody (4A11) [H00029780-M01] - Analysis of PARVB expression in transfected 293T cell line by PARVB monoclonal antibody (M01), clone 4A11.Lane 1: PARVB transfected lysate(40.25 KDa).Lane 2: Non-transfected lysate.

Monoclonal Anti-PARVB antibody produced in mouse - WH0029780M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A11
<B>Immunoblotting</B><BR/>Monoclonal Anti-PARVB, <B>Cat. No. WH0029780M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~64.61 kDa using immunogen protein lysate.

Anti-PARVB (ab1) antibody produced in rabbit - SAB2101724 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PARVB (ab1): <B>Cat. No.SAB2101724</B>: PARVB in Transfected 293T cell lysate with PARVB antibody at 1.0 μg/mL.

Monoclonal Anti-PARVB antibody produced in mouse - SAB4100578 from Sigma-Aldrich

Prices $377.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone PARVB-A549

PARVB antibody - N-terminal region (ARP46017_P050) - ARP46017_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PARVB antibody - C-terminal region (ARP46018_P050) - ARP46018_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PARVB-Antibody-monoclonal-M01 - AT3184a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A11
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (64.24 KDa) .

PARVB antibody, C-term - GTX46496 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
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