| Gene Symbol |
EIF2AK4
|
| Entrez Gene |
440275
|
| Alt Symbol |
GCN2, PVOD2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation initiation factor 2 alpha kinase 4
|
| Other Description |
GCN2 eIF2alpha kinase|GCN2-like protein|eukaryotic translation initiation factor 2-alpha kinase 4|general control nonderepressible 2
|
| Swissprots |
Q9NSQ3 Q6DC97 Q9P2K8 Q9H5K1 C9JEC4 Q9NSZ5 Q69YL7 Q9UJ56 Q96GN6
|
| Accessions |
EAW92388 Q9P2K8 AB037759 BAA92576 AJ243428 CAB58360 AK027011 BAB15625 AK074361 AL137627 CAB70849 AL137676 AL157497 CAB75678 AL832907 CAH10626 BC009350 AAH09350 BC014915 BC019914 BC061591 BC078179 AAH78179 BC146319 AAI46320 BX649048 CN286138 XM_005254392 XP_005254449 XM_011521599 XP_011519901 XM_011521600 XP_011519902 NM_001013703 NP_001013725
|
| Function |
Can phosphorylate the alpha subunit of EIF2 and may mediate translational control. {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Expressed in the lung in smooth muscle cells of the pulmonary vessel wall, interstitial tissue and macrophages. {ECO:0000269|PubMed:10504407, ECO:0000269|PubMed:24292273}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum, Hepatitis C, Influenza A, Measles, Herpes simplex infection
|