EIF2AK4

Gene Symbol	EIF2AK4
Entrez Gene	440275
Alt Symbol	GCN2, PVOD2
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 2 alpha kinase 4
Other Description	GCN2 eIF2alpha kinase|GCN2-like protein|eukaryotic translation initiation factor 2-alpha kinase 4|general control nonderepressible 2
Swissprots	Q9NSQ3 Q6DC97 Q9P2K8 Q9H5K1 C9JEC4 Q9NSZ5 Q69YL7 Q9UJ56 Q96GN6
Accessions	EAW92388 Q9P2K8 AB037759 BAA92576 AJ243428 CAB58360 AK027011 BAB15625 AK074361 AL137627 CAB70849 AL137676 AL157497 CAB75678 AL832907 CAH10626 BC009350 AAH09350 BC014915 BC019914 BC061591 BC078179 AAH78179 BC146319 AAI46320 BX649048 CN286138 XM_005254392 XP_005254449 XM_011521599 XP_011519901 XM_011521600 XP_011519902 NM_001013703 NP_001013725
Function	Can phosphorylate the alpha subunit of EIF2 and may mediate translational control. {ECO:0000250}.
Tissue Specificity	Widely expressed. Expressed in the lung in smooth muscle cells of the pulmonary vessel wall, interstitial tissue and macrophages. {ECO:0000269|PubMed:10504407, ECO:0000269|PubMed:24292273}.
Top Pathways	Protein processing in endoplasmic reticulum, Hepatitis C, Influenza A, Measles, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GCN2 protein fragment - ab153650 from Abcam Category Protein Source Wheat germ Species Human

Human GCN2 protein fragment - ab112408 from Abcam Category Protein Source Wheat germ Species Human

GCN2 Antibody Blocking Peptide - LS-E3519 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GCN2 Antibody Blocking Peptide - LS-E8707 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GCN2 Protein - H00440275-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GCN2 Protein - H00440275-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GCN2-Antibody-N-term-G11-Blocking-peptide - BP7130a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCN2-Antibody-Center-F1116-Blocking-Peptide - BP8062a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EIF2AK4 / GCN2 - H00440275-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EIF2AK4 / GCN2 - H00440275-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EIF2AK4 / GCN2 - H00440275-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

EIF2AK4 / GCN2 - H00440275-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

EIF2AK4 / GCN2 - P5554 from Acris Antibodies Category Protein Prices $790.00 Sizes 5 µg Species Human

EIF2AK4 fusion protein - ag1654 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human EIF2AK4 - EIF2AK4-28160TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4, GST-tagged - EIF2AK4-1011H from Creative Biomart Category Protein Species Human

GCN2, active - 14-934 from EMD Millipore Prices $380.00 Sizes 10 µg also available in 250μg size as catalog # 14-934m and in bulk as catalog # 14-934-k. Source N-terminal GST-tagged, recombinant, human GCN2 full length, expressed by baculovirus in Sf21 insect cells. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626.

GCN2, active - 14-934-K from EMD Millipore Source N-terminal GST-tagged, recombinant, human GCN2 full length, expressed by baculovirus in Sf21 insect cells. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626. Species Human

Recombinant Human Eukaryotic translation initiation factor 2-alpha kinase 4(EIF2AK4) ,partial - CSB-YP868396HU CSB-EP868396HU CSB-BP868396HU CSB-MP868396HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GCN2 Recombinant Protein Antigen - NBP2-38126PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GCN2, active - 14-934M from EMD Millipore Prices $2,441.00 Sizes 250 µg also available in 10μg size as catalog # 14-934 and in bulk as catalog # 14-934-k. Source N-terminal GST-tagged, recombinant, human GCN2 full length, expressed by baculovirus in Sf21 insect cells. The recombinant protein contains the amino acid substitution E556G with reference to GenPept NP_001013725. E556G is reported in GenPept CAH10626.

GCN2-Antibody-Center-D762-Blocking-Peptide - BP7130c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCN2-Antibody--N-term-R181-Blocking-Peptide - BP7130b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EIF2AK4 Peptide, Human - M34GP04799H from Creative Peptides Category Peptide Source Synthetic. Species Human

Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4), partial, Recombinant Protein - MBS1354768 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,450.00, $1,450.00, $1,925.00, $1,925.00, $2,385.00, $2,385.00, $2,420.00, $3,800.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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