EIF2AK4

Gene Symbol	EIF2AK4
Entrez Gene	440275
Alt Symbol	GCN2, PVOD2
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 2 alpha kinase 4
Other Description	GCN2 eIF2alpha kinase|GCN2-like protein|eukaryotic translation initiation factor 2-alpha kinase 4|general control nonderepressible 2
Swissprots	Q9NSQ3 Q6DC97 Q9P2K8 Q9H5K1 C9JEC4 Q9NSZ5 Q69YL7 Q9UJ56 Q96GN6
Accessions	EAW92388 Q9P2K8 AB037759 BAA92576 AJ243428 CAB58360 AK027011 BAB15625 AK074361 AL137627 CAB70849 AL137676 AL157497 CAB75678 AL832907 CAH10626 BC009350 AAH09350 BC014915 BC019914 BC061591 BC078179 AAH78179 BC146319 AAI46320 BX649048 CN286138 XM_005254392 XP_005254449 XM_011521599 XP_011519901 XM_011521600 XP_011519902 NM_001013703 NP_001013725
Function	Can phosphorylate the alpha subunit of EIF2 and may mediate translational control. {ECO:0000250}.
Tissue Specificity	Widely expressed. Expressed in the lung in smooth muscle cells of the pulmonary vessel wall, interstitial tissue and macrophages. {ECO:0000269|PubMed:10504407, ECO:0000269|PubMed:24292273}.
Top Pathways	Protein processing in endoplasmic reticulum, Hepatitis C, Influenza A, Measles, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GCN2 CRISPR/Cas9 KO Plasmid (h) - sc-402313 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 HDR Plasmid (h) - sc-402313-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 Double Nickase Plasmid (h) - sc-402313-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 Double Nickase Plasmid (h2) - sc-402313-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 CRISPR Activation Plasmid (h) - sc-402313-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 CRISPR Activation Plasmid (h2) - sc-402313-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 Lentiviral Activation Particles (h) - sc-402313-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 Lentiviral Activation Particles (h2) - sc-402313-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GCN2 siRNA (h) - sc-45644 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCN2 shRNA Plasmid (h) - sc-45644-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCN2 shRNA (h) Lentiviral Particles - sc-45644-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GCN2 RNAi - H00440275-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU053951 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0669 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0671 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0670 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN7743 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7743 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04769 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04769

EIF2AK4 siRNA (Human) - CRJ8244 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

EIF2AK4 - MBS828979 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human EIF2AK4 (NM_001013703.2) - SHH284241 from Creative biogene Category siRNA Species Reactivities Human

Human EIF2AK4 siRNA - orb278745 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

EIF2AK4 shRNA Plasmid (Human) - CHJ8244 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

EIF2AK4 miRNA 3'UTR clone - MiUTR1H-03155 from Creative biogene Species Reactivities Human

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