DMP1

Gene Symbol DMP1
Entrez Gene 1758
Alt Symbol ARHP, ARHR, DMP-1
Species Human
Gene Type protein-coding
Description dentin matrix acidic phosphoprotein 1
Other Description dentin matrix protein 1
Swissprots A1L4L3 Q13316 O43265
Accessions AAA97602 EAX05996 EAX05997 Q13316 AI371158 BC130581 AAI30582 BC132865 AAI32866 H89203 HQ258290 ADR83044 U65378 AAB87728 U89012 AAC51332 XM_011531705 XP_011530007 XM_011531706 XP_011530008 NM_001079911 NP_001073380 NM_004407 NP_004398
Function May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. {ECO:0000269|PubMed:12615915}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12615915}. Cytoplasm {ECO:0000269|PubMed:12615915}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12615915}. Note=In proliferating preosteoblasts it is nuclear, during early maturation stage is cytoplasmic and in mature osteoblast localizes in the mineralized matrix. Export from the nucleus of differentiating osteoblast is triggered by the release of calcium from intracellular stores followed by a massive influx of this pool of calcium into the nucleus.
Tissue Specificity Expressed in tooth particularly in odontoblast, ameloblast and cementoblast.

DMP-1 (LFMb-31) - sc-73633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DMP-1 (LFMb-31): sc-73633. Western blot analysis of human recombinant DMP-1.

Anti-DMP1 antibody - ab103203 from Abcam

Prices $388.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DMP1 antibody (ab103203) at 1 µg/ml + Bone Marrow (Human) Tissue Lysate - adult normal tissue at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-DMP1 antibody - ab82351 from Abcam

Prices $387.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab82351 staining DMP1 in human tooth tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde, permeabilized with methanol and blocked with 5% BSA for 1 hour at 25°C. Samples were incubated with primary antibody (1/100) for 24 hours at 4°C. An undiluted HRP-conjugated goat anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-DMP1 antibody - ab76632 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-DMP1 antibody (ab76632) at 1 µg/ml + Recombinant tagged human DMP1 fragment at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-DMP1 antibody - ab81985 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-DMP1 antibody (ab81985) at 1 µg/ml + human kidney lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-DMP1 antibody - N-terminal - ab139154 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DMP1 antibody - N-terminal (ab139154) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-DMP1 Antibody - LS-C64930 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-DMP1 Antibody (aa221-331) - LS-C128655 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DMP1 Antibody - LS-C143822 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-DMP1 Antibody (clone 11D61, Biotin) - LS-C183826 from LifeSpan Bioscience

Prices $650.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 11D61

Anti-DMP1 Antibody (aa21) - LS-C190194 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175, AP) - LS-C213594 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175, APC) - LS-C213596 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa228-239) - LS-C87351 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-DMP1 Antibody (aa146-175, Biotin) - LS-C213597 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175, Azide-free, HRP) - LS-C213599 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175, FITC) - LS-C213598 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175, PE) - LS-C213600 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa130-159) - LS-C320864 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody - LS-C341999 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DMP1 Antibody (aa146-175) - LS-C159466 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DMP1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The DMP1 antibody detected the DMP1 protein (arrow).

Anti-DMP1 Antibody IHC-plus™ - LS-B11226 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DMP1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11226 concentration 5 ug/ml.

Anti-DMP1 Antibody - LS-C334591 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using DMP1 antibody.

Anti-DMP1 Antibody (clone 1D4) - LS-C197061 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4
Immunofluorescence of monoclonal antibody to DMP1 on HeLa cell . [antibody concentration 10 ug/ml]

DMP-1 Antibody - NBP1-89484 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: DMP-1 Antibody [NBP1-89484] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & vesicles.
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