DMP1

Gene Symbol	DMP1
Entrez Gene	1758
Alt Symbol	ARHP, ARHR, DMP-1
Species	Human
Gene Type	protein-coding
Description	dentin matrix acidic phosphoprotein 1
Other Description	dentin matrix protein 1
Swissprots	A1L4L3 Q13316 O43265
Accessions	AAA97602 EAX05996 EAX05997 Q13316 AI371158 BC130581 AAI30582 BC132865 AAI32866 H89203 HQ258290 ADR83044 U65378 AAB87728 U89012 AAC51332 XM_011531705 XP_011530007 XM_011531706 XP_011530008 NM_001079911 NP_001073380 NM_004407 NP_004398
Function	May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. {ECO:0000269|PubMed:12615915}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12615915}. Cytoplasm {ECO:0000269|PubMed:12615915}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12615915}. Note=In proliferating preosteoblasts it is nuclear, during early maturation stage is cytoplasmic and in mature osteoblast localizes in the mineralized matrix. Export from the nucleus of differentiating osteoblast is triggered by the release of calcium from intracellular stores followed by a massive influx of this pool of calcium into the nucleus.
Tissue Specificity	Expressed in tooth particularly in odontoblast, ameloblast and cementoblast.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DMP1 peptide - ab103554 from Abcam Category Peptide

Human DMP1 peptide - ab103555 from Abcam Category Peptide

Human DMP1 protein fragment - ab158291 from Abcam Category Protein Source Wheat germ Species Human

DMP1 Antibody Blocking Peptide - LS-E6279 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DMP1 Antibody Blocking Peptide - LS-E26855 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DMP-1 Partial Recombinant Protein - H00001758-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DMP1-Antibody-N-term-Blocking-Peptide - BP18965a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DMP1 blocking peptide - GTX88597-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human DMP-1, CF - 4129-DM-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Tyr497 & Asp202-Tyr497, both with a C-terminal 6-His tag & Leu17-Ser201

Recombinant Mouse DMP-1, CF - 4386-DM-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu17-Tyr503, with a C-terminal 6-His tag

Human DMP-1 protein - orb180246 from Biorbyt Category Protein Prices $213.00, $391.00, $808.00, $1,122.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

DMP1 Blocking Peptide - 33R-10953 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

DMP1 Peptide - AC21-1688-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DMP1 - H00001758-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DMP1 - H00001758-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DMP1 Peptide - 46-832P from ProSci Category Peptide Species Human

DMP1 fusion protein - ag20064 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DMP1, His tagged - DMP1-3790H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human DMP1 - DMP1-503H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human DMP1, His-tagged - DMP1-662H from Creative Biomart Category Protein Source NSO cells Species Human

DMP1 - PN201487 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Human DMP1 Protein (His Tag) - 11929-H08H-50 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Human Dentin matrix acidic phosphoprotein 1(DMP1) - CSB-YP006967HU CSB-EP006967HU CSB-BP006967HU CSB-MP006967HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DMP1 Blocking Peptide - 3844BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 µg

Recombinant Mouse DMP-1 Protein, CF - 4386-DM from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Leu17-Tyr503, with a C-terminal 6-His tag Species Mouse

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