Gene Symbol | SLC6A20 |
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Entrez Gene | 54716 |
Alt Symbol | SIT1, XT3, Xtrp3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (proline IMINO transporter), member 20 |
Other Description | X transporter protein 3|neurotransmitter transporter RB21A|orphan transporter XT3|sodium- and chloride-dependent transporter XTRP3|sodium/imino-acid transporter 1|solute carrier family 6 (neurotransmitter transporter), member 20|transporter rB21A homolog |
Swissprots | Q9NPQ2 Q8TF10 Q9NQ77 O75590 Q9NP91 A1A4F2 |
Accessions | CAB96872 EAW64747 EAW64748 Q9NP91 AF075260 AAC27755 AF125107 AAL75944 AJ276207 CAB99310 AJ276208 CAB99311 AL389979 CAB97535 BC036073 BC126197 AAI26198 BC136431 AAI36432 BC144087 AAI44088 DR006419 EL949345 HQ258580 ADR83334 XM_005265236 XP_005265293 XM_011533847 XP_011532149 XM_011533848 XP_011532150 NM_020208 NP_064593 NM_022405 NP_071800 |
Function | Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. Involved in the transport of glycine. {ECO:0000269|PubMed:15632147, ECO:0000269|PubMed:19033659}. |
Subcellular Location | Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Note=Located in the apical brush border membrane of kidney proximal tubule cells. {ECO:0000250}. |
Tissue Specificity | Kidney and small intestine. Expressed in the S3 segment of the proximal tubule. {ECO:0000269|PubMed:19033659, ECO:0000269|PubMed:9932288}. |
XTRP3 (Y-12) - sc-49580 from Santa Cruz Biotechnology
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XTRP3 (H-73) - sc-134762 from Santa Cruz Biotechnology
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Anti-SLC6A20 antibody - ab57408 from Abcam
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SLC6A20 Antibody - NBP1-80612 from Novus Biologicals
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SIT1 Antibody - NBP2-13311 from Novus Biologicals
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SIT1 Antibody (SIT-40) - NB100-78461 from Novus Biologicals
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SLC6A20 Antibody (3G6) - H00054716-M02 from Novus Biologicals
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SLC6A20 Antibody - H00054716-A01 from Novus Biologicals
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Monoclonal Anti-SLC6A20 antibody produced in mouse - WH0054716M2 from Sigma-Aldrich
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Anti-SLC6A20 antibody produced in rabbit - HPA029873 from Sigma-Aldrich
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SIT1 Antibody - abx029063 from Abbexa
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SLC6A20 antibody - H00054716-A01 from Acris Antibodies
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SLC6A20 antibody - H00054716-B01P from Acris Antibodies
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SLC6A20 antibody - H00054716-M02 from Acris Antibodies
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SLC6A20 antibody - 25919-1-AP from Proteintech Group
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SLC6A20, Monoclonal Antibody - MBS6010238 from MyBioSource
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Anti-SLC6A20 (aa 301-369) polyclonal antibody - DPAB-DC2356 from Creative Diagnostics
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SIT1, Polyclonal Antibody - MBS6004817 from MyBioSource
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Anti-solute carrier family 6 (proline IMINO transporter), member 20 - 08A054716 from MP Biomedicals
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XTRP3 (C-11) - sc-515119 from Santa Cruz Biotechnology
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Mouse Anti-Human SIT1/SHP2 interacting TRAP SIT Clone SIT-01 mAb - MON4021 from Cell Science
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SLC6A20 antibody - orb338722 from Biorbyt
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SLC6A20 Antibody - 46250 from Signalway Antibody
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SLC6A20 Antibody - DF9926 from Affinity Biosciences
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Anti-SIT1 Goat Antibody - EB09881 from ARP American Research Products
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