Gene Symbol | SLC6A20 |
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Entrez Gene | 54716 |
Alt Symbol | SIT1, XT3, Xtrp3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (proline IMINO transporter), member 20 |
Other Description | X transporter protein 3|neurotransmitter transporter RB21A|orphan transporter XT3|sodium- and chloride-dependent transporter XTRP3|sodium/imino-acid transporter 1|solute carrier family 6 (neurotransmitter transporter), member 20|transporter rB21A homolog |
Swissprots | Q9NPQ2 Q8TF10 Q9NQ77 O75590 Q9NP91 A1A4F2 |
Accessions | CAB96872 EAW64747 EAW64748 Q9NP91 AF075260 AAC27755 AF125107 AAL75944 AJ276207 CAB99310 AJ276208 CAB99311 AL389979 CAB97535 BC036073 BC126197 AAI26198 BC136431 AAI36432 BC144087 AAI44088 DR006419 EL949345 HQ258580 ADR83334 XM_005265236 XP_005265293 XM_011533847 XP_011532149 XM_011533848 XP_011532150 NM_020208 NP_064593 NM_022405 NP_071800 |
Function | Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. Involved in the transport of glycine. {ECO:0000269|PubMed:15632147, ECO:0000269|PubMed:19033659}. |
Subcellular Location | Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Note=Located in the apical brush border membrane of kidney proximal tubule cells. {ECO:0000250}. |
Tissue Specificity | Kidney and small intestine. Expressed in the S3 segment of the proximal tubule. {ECO:0000269|PubMed:19033659, ECO:0000269|PubMed:9932288}. |
Human SLC6A20 protein fragment - ab162821 from Abcam
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SIT1 Antibody Blocking Peptide - LS-E4470 from LifeSpan Bioscience
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SIT1 Antibody Blocking Peptide - LS-E27307 from LifeSpan Bioscience
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Recombinant Human SLC6A20 Protein - H00054716-Q01 from Novus Biologicals
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Recombinant Human SIT1 Protein - NBP1-72451 from Novus Biologicals
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SIT1 Recombinant Protein - P4317 from Novus Biologicals
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Recombinant Human SLC6A20 Protein - H00054716-G01-10ug from Novus Biologicals
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SLC6A20-Antibody-C-term-Blocking-peptide - BP13608b from Abgent, a WuXi AppTec company
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Human SIT1 protein - orb169299 from Biorbyt
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SIT1 protein (His tag) - 80R-1965 from Fitzgerald
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SLC6A20 - H00054716-Q01-10 from Acris Antibodies
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SLC6A20 - H00054716-Q01-25 from Acris Antibodies
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SLC6A20 fusion protein - Ag23194 from Proteintech Group
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SIT1 Protein - NBP2-13311PEP from Novus Biologicals
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SLC6A20 Protein - NBP1-80612PEP from Novus Biologicals
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Human SIT1 protein - orb49654 from Biorbyt
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SIT1 Peptide, Human - M34GP14274H from Creative Peptides
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Sodium- and chloride-dependent transporter XTRP3 (SLC6A20), Recombinant Protein - MBS7099347 from MyBioSource
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SIT1 Immunizing peptide - orb17802 from Biorbyt
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