MX1

Gene Symbol MX1
Entrez Gene 4599
Alt Symbol IFI-78K, IFI78, MX, MxA
Species Human
Gene Type protein-coding
Description MX dynamin-like GTPase 1
Other Description interferon-induced GTP-binding protein Mx1|interferon-induced protein p78|interferon-inducible protein p78|interferon-regulated resistance GTP-binding protein MxA|myxoma resistance protein 1|myxovirus (influenza virus) resistance 1, interferon-inducible protein p78
Swissprots D3DSI8 C9IYV7 Q96CI3 C9J8D6 B2RDA5 B3KU10 P20591 Q86YP5 C9JN19 C9JZS6 C9JN88 C9JUL1
Accessions AAD43063 CAB90556 EAX09600 EAX09601 EAX09602 EAX09603 EAX09604 P20591 A00209 CAA00041 AK093008 BAC04017 AK096355 BAG53272 AK225885 AK315465 BAG37852 AY186254 AAO31807 BC014222 AAH14222 BC032602 AAH32602 BC052255 CB151486 DA351922 DA726666 EB388095 JF432729 ADZ15946 M30817 AAA36337 M33882 AAA36458 XM_005260978 XP_005261035 XM_005260979 XP_005261036 XM_005260980 XP_005261037 XM_005260981 XP_005261038 XM_005260982 XP_005261039 XM_011529568 XP_011527870 XM_011529569 XP_011527871 XM_011529570 XP_011527872 NM_001144925 NP_001138397 NM_001178046 NP_001171517 NM_001282920 NP_001269849 NM_002462 NP_002453
Function Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs. {ECO:0000269|PubMed:11880649, ECO:0000269|PubMed:14687945, ECO:0000269|PubMed:14752052, ECO:0000269|PubMed:15047845, ECO:0000269|PubMed:15355513, ECO:0000269|PubMe
Subcellular Location Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids. Colocalizes with CCHFV protein N in the perinuclear region.
Top Pathways Measles, Influenza A

Mx1 (E-8) - sc-398564 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mx1 (E-8): sc-398564. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (C-12) - sc-271399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mx1/2/3 (C-12): sc-271399. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (D-14) - sc-34128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mx1/2/3 (D-14): sc-34128. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and mouse Mx1 transfected: sc-121876 (B) 293T whole cell lysates.

Mx1/2/3 (E-5) - sc-271024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mx1/2/3 (E-5): sc-271024. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (G-16) - sc-34130 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mx1/2/3 (G-16): sc-34130. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (H-285) - sc-50509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Mx1/2/3 (H-285): sc-50509. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (K-19) - sc-34131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mx1/2/3 (K-19): sc-34131. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Mx1/2/3 (C-1) - sc-166412 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Mx1/2/3 (C-1): sc-166412. Western blot analysis of Mx1 expression in non-transfected: sc-117752 (A) and human Mx1 transfected: sc-115203 (B) 293T whole cell lysates.

Anti-MX1 antibody - ab95926 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MX1 antibody (ab95926) at 1/5000 dilutionLane 1 : H1299 cell lysateLane 2 : HeLa cell lysateLane 3 : Raji cell lysateLysates/proteins at 30 µg per lane.

Anti-MX1 antibody - ab198178 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MX1 antibody (ab198178) at 1/200 dilution + HeLa cell lysate at 40 µg

Anti-MX1 antibody - ab197205 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MX1 antibody (ab197205) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : Raji cell lysateLane 3 : 293T cell lysate

Anti-MX1 antibody - ab97921 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MX1 antibody (ab97921) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-MX1 antibody - ab124033 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MX1 antibody (ab124033) at 1/100 dilution + T47D cell line lysate at 35 µg

Anti-MX1 / MX Antibody (aa68-303) - LS-C315027 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MX1 / MX.

Anti-MX1 / MX Antibody - LS-C331685 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of mouse spleen tissue, using MX1 antibody.

Anti-MX1 / MX Antibody (aa1-662) - LS-C130853 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MX1 / MX Antibody (C-Terminus) - LS-C80814 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-MX1 / MX Antibody (clone 474CT4.1.5, AP) - LS-C206332 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 474CT4.1.5

Anti-MX1 / MX Antibody (clone 474CT4.1.5, APC) - LS-C206334 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 474CT4.1.5

Anti-MX1 / MX Antibody (clone 474CT4.1.5, Biotin) - LS-C206336 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 474CT4.1.5

Anti-MX1 / MX Antibody (aa617-646) - LS-C158334 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
MX1 Antibody western blot of T47D cell line lysates (35 ug/lane). The MX1 antibody detected the MX1 protein (arrow).

Anti-MX1 / MX Antibody (aa617-646) - LS-C158333 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
MX1 Antibody western blot of T47D cell line lysates (35 ug/lane). The MX1 antibody detected the MX1 protein (arrow).

Anti-MX1 / MX Antibody (clone 474CT4.1.5, FITC) - LS-C206338 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 474CT4.1.5

Anti-MX1 / MX Antibody (clone 474CT4.1.5, PE) - LS-C206339 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 474CT4.1.5

Anti-MX1 / MX Antibody (aa408-437, APC) - LS-C207283 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more