MX1

Gene Symbol	MX1
Entrez Gene	4599
Alt Symbol	IFI-78K, IFI78, MX, MxA
Species	Human
Gene Type	protein-coding
Description	MX dynamin-like GTPase 1
Other Description	interferon-induced GTP-binding protein Mx1|interferon-induced protein p78|interferon-inducible protein p78|interferon-regulated resistance GTP-binding protein MxA|myxoma resistance protein 1|myxovirus (influenza virus) resistance 1, interferon-inducible protein p78
Swissprots	D3DSI8 C9IYV7 Q96CI3 C9J8D6 B2RDA5 B3KU10 P20591 Q86YP5 C9JN19 C9JZS6 C9JN88 C9JUL1
Accessions	AAD43063 CAB90556 EAX09600 EAX09601 EAX09602 EAX09603 EAX09604 P20591 A00209 CAA00041 AK093008 BAC04017 AK096355 BAG53272 AK225885 AK315465 BAG37852 AY186254 AAO31807 BC014222 AAH14222 BC032602 AAH32602 BC052255 CB151486 DA351922 DA726666 EB388095 JF432729 ADZ15946 M30817 AAA36337 M33882 AAA36458 XM_005260978 XP_005261035 XM_005260979 XP_005261036 XM_005260980 XP_005261037 XM_005260981 XP_005261038 XM_005260982 XP_005261039 XM_011529568 XP_011527870 XM_011529569 XP_011527871 XM_011529570 XP_011527872 NM_001144925 NP_001138397 NM_001178046 NP_001171517 NM_001282920 NP_001269849 NM_002462 NP_002453
Function	Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs. {ECO:0000269|PubMed:11880649, ECO:0000269|PubMed:14687945, ECO:0000269|PubMed:14752052, ECO:0000269|PubMed:15047845, ECO:0000269|PubMed:15355513, ECO:0000269|PubMe
Subcellular Location	Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids. Colocalizes with CCHFV protein N in the perinuclear region.
Top Pathways	Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MX1 / MX ELISA Kit (Sandwich ELISA) - LS-F7459 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 1.56-100 ng/ml

Human MX1 ELISA Kit - abx152409 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Interferon-induced GTP-binding protein Mx1 (MX1), Human, ELISA Kit - CSB-EL015249HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Interferon-induced GTP-binding protein Mx1 (MX1), Human, ELISA Kit - E01I0454 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

MX1 (Myxovirus Resistance 1), Human, ELISA Kit - E-EL-H2379 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t Sensitivity 0.188 ng/mL Range 0.313-20ng/mL

Myxovirus Resistance 1 (MX1), Human, ELISA Kit - SEL763Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.060ng/mL Range 0.156-10ng/mL

Myxovirus Resistance 1, MX1, Rabbit, ELISA Kit - E-EL-RB0622 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Myxovirus Resistance 1, MX1, Chicken, ELISA Kit - E-EL-Ch0905 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Myxovirus Resistance 1, MX1, Porcine, ELISA Kit - E-EL-P1933 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Myxovirus Resistance 1, MX1, Sheep, ELISA Kit - E-EL-S0957 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Myxovirus Resistance 1, MX1, Monkey, ELISA Kit - E-EL-MK1685 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

MX1, ELISA Kit - MBS2509987 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Human MxA Protein ELISA Kit - DEIA4736 from Creative Diagnostics Category ELISA Kit

Human MX1 (Myxovirus Resistance 1) ELISA Kit - E-EL-H2379 from Elabscience Category ELISA Kit Sensitivity 0.188ng/mL Range 0.313~20ng/mL

Human MX1 (Myxovirus Resistance 1) CLIA Kit - E-CL-H1384 from Elabscience Category CLIA Kit Sensitivity 0.188ng/mL Range 0.313~20ng/mL

Interferon-induced GTP-binding protein Mx1, ELISA Kit - MBS282520 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1, ELISA Kit - MBS282860 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS2602265 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS2602021 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS2601770 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS7232314 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS7226429 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS7202369 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS7230297 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon-induced GTP-binding protein Mx1 (MX1), ELISA Kit - MBS7218016 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

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