Gene Symbol | SYNGAP1 |
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Entrez Gene | 8831 |
Alt Symbol | MRD5, RASA1, RASA5, SYNGAP |
Species | Human |
Gene Type | protein-coding |
Description | synaptic Ras GTPase activating protein 1 |
Other Description | Ras GTPase-activating protein SynGAP|neuronal RasGAP|ras/Rap GTPase-activating protein SynGAP|synaptic Ras GTPase activating protein 1 homolog|synaptic Ras GTPase activating protein, 135kDa|synaptic Ras GTPase-activating protein 1 |
Swissprots | A8MQC4 A2BEL7 Q9UGE2 Q96PV0 Q8TCS2 A2BEL6 A2AB17 |
Accessions | CAA16161 EAX03735 EAX03736 EAX03737 EAX03738 Q96PV0 AK094225 AK124666 AK307888 AL713634 CAD28452 BC148357 AAI48358 BM354009 BX282051 CN412954 DA057307 NM_006772 NP_006763 NM_001130066 |
Function | Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity). {ECO:0000250}. |
Human SynGAP protein fragment - ab152921 from Abcam
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Rat SynGAP (phospho S1123) peptide - ab16982 from Abcam
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Rat SynGAP peptide - ab16987 from Abcam
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RASA1 Antibody Blocking Peptide - LS-E2062 from LifeSpan Bioscience
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RASA1 Antibody Blocking Peptide - LS-E15485 from LifeSpan Bioscience
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SYNGAP Antibody Blocking Peptide - LS-E23481 from LifeSpan Bioscience
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SYNGAP Antibody Blocking Peptide - LS-E27770 from LifeSpan Bioscience
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SYNGAP Antibody Blocking Peptide - LS-E27771 from LifeSpan Bioscience
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Recombinant Human RAS p21 Protein - H00005921-Q01 from Novus Biologicals
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Recombinant Human RAS p21 Protein - H00005921-P01 from Novus Biologicals
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Recombinant Human SynGAP Protein - H00008831-Q01 from Novus Biologicals
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SYNGAP1 blocking peptide - GTX89266-PEP from GeneTex
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Rasa1 Blocking Peptide - 33R-8652 from Fitzgerald
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synGAP Peptide - AC21-2582-P from Abcore
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synGAP Peptide - AC21-2583-P from Abcore
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SYNGAP1 - H00008831-Q01-10 from Acris Antibodies
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SYNGAP1 - H00008831-Q01-25 from Acris Antibodies
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SYNGAP1 Peptide - 42-895P from ProSci
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SYNGAP1 Peptide - 42-896P from ProSci
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Recombinant Human Ras GTPase-activating protein SynGAP(SYNGAP1) ,partial - CSB-YP857006HU CSB-EP857006HU CSB-BP857006HU CSB-MP857006HU from Cusabio
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SYNGAP1, Peptide - MBS428389 from MyBioSource
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SYNGAP1, Peptide - MBS427468 from MyBioSource
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SynGAP Recombinant Protein Antigen - NBP2-34046PEP from Novus Biologicals
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RASA1 Peptide, Human - M34GP12984H from Creative Peptides
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SYNGAP1 Peptide, Human - M34GP15472H from Creative Peptides
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