SYNGAP1

Gene Symbol SYNGAP1
Entrez Gene 8831
Alt Symbol MRD5, RASA1, RASA5, SYNGAP
Species Human
Gene Type protein-coding
Description synaptic Ras GTPase activating protein 1
Other Description Ras GTPase-activating protein SynGAP|neuronal RasGAP|ras/Rap GTPase-activating protein SynGAP|synaptic Ras GTPase activating protein 1 homolog|synaptic Ras GTPase activating protein, 135kDa|synaptic Ras GTPase-activating protein 1
Swissprots A8MQC4 A2BEL7 Q9UGE2 Q96PV0 Q8TCS2 A2BEL6 A2AB17
Accessions CAA16161 EAX03735 EAX03736 EAX03737 EAX03738 Q96PV0 AK094225 AK124666 AK307888 AL713634 CAD28452 BC148357 AAI48358 BM354009 BX282051 CN412954 DA057307 NM_006772 NP_006763 NM_001130066
Function Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity). {ECO:0000250}.

SynGAP (D20C7) Rabbit mAb - 5539 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D20C7
Western blot analysis of extracts from mouse and rat brain tissue using SynGAP (D20C7) Rabbit mAb.

SynGAP (D78B11) Rabbit mAb - 5540 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D78B11
Western blot analysis of extracts from mouse and rat brain using SynGAP (D78B11) Rabbit mAb.

SynGAP (D88G1) Rabbit mAb - 9479 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D88G1
Western blot analysis of extracts from mouse and rat brain tissue using SynGAP (D88G1) Rabbit mAb.

SynGAP Antibody - 3200 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and rat brain tissue using SynGAP Antibody.

SynGAP (S-20) - sc-8571 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SynGAP (S-20): sc-8571. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic staining of myocytes.

SynGAP (H-210) - sc-33598 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SynGAP (phospho S1123) antibody - ab16649 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immuofluorescent staining for SynGap phospho S1123 in the hippocampus of a naïve rat using antibody ab16649. [A] Immunostaining was observed in the cytoplasm of a few hippocampal neurons (Picture taken with a X10 objective). Higher power magnification of the same hippocampal section is shown in image B (X 40 objective). Tissue preparation: rat brain tissue was perfusion fixed (4% PFA) followed by post fix and cryoprotection in 20% sucrose before freezing in OCT. 30µm coronal sections were cut on a cryostat for free floating IHC. Primary antibody ab16649 was used at 1/3000 (0.2µg/ml) incubated overnight at room temperature. Secondary antibody used: anti-rabbit Alexa fluor 488 (1/1000) incubated for 2 hours at room temperature.

Anti-SynGAP antibody - ab3344 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunolocalization of SynGAP in rat hippocampal neurons using ab3344.

Anti-SynGAP antibody - ab126871 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-SynGAP antibody (ab126871) at 2 µg/ml + Mouse Brain lysate at 35 µgdeveloped using the ECL technique

Anti-SynGAP antibody - ab128630 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SynGAP antibody (ab128630) at 1 µg/ml + Human fetal kidney lysate at 10 µg

Anti-SynGAP antibody [EPR2883Y] - ab77235 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2883Y
Anti-SynGAP antibody [EPR2883Y] (ab77235) at 1/1000 dilution + fetal brain lysate at 10 µgSecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-SYNGAP Antibody (Arg1070, clone NOD-15) - LS-C191323 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone NOD-15

Anti-SYNGAP Antibody (Arg710, clone NOD-15) - LS-C191322 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone NOD-15

Anti-SYNGAP Antibody (aa1177-1226) - LS-C151709 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SYNGAP antibody Western Blot of Fetal kidney.

Anti-SYNGAP Antibody - LS-C335384 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain cell line, using SYNGAP1 antibody.

Anti-SYNGAP Antibody (aa60-72) - LS-C154908 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SYNGAP1 antibody (2 ug/ml) staining of Mouse Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SYNGAP Antibody (aa1169-1183) - LS-C154907 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SYNGAP1 antibody (0.03 ug/ml) staining of Mouse Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SYNGAP Antibody (C-Terminus, clone EP3081Y) - LS-C105437 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3081Y
Western blot analysis on fetal brain lysate using anti-SynGAP antibody (LS-C105437), dilution 1:1000.

SynGAP Antibody - NBP2-34046 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SynGAP Antibody - NBP1-87841 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SynGAP Antibody [NBP1-87841] - Staining of human cell line A-431 shows positivity in nucleus.

SynGAP Antibody - NBP2-27541 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SynGAP Antibody [NBP2-27541] - (0.03 ug/ml) staining of Mouse Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SynGAP Antibody - NBP2-27558 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SynGAP Antibody [NBP2-27558] - NBP2-27558 (2ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SynGAP (Ser836) Polyclonal Antibody - bs-10392R from Bioss

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Synaptic Ras-GAP 1 Polyclonal Antibody - bs-11369R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SynGAP (Ser836) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10392R-A350 from Bioss

Prices $389.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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