SYNGAP1

Gene Symbol SYNGAP1
Entrez Gene 8831
Alt Symbol MRD5, RASA1, RASA5, SYNGAP
Species Human
Gene Type protein-coding
Description synaptic Ras GTPase activating protein 1
Other Description Ras GTPase-activating protein SynGAP|neuronal RasGAP|ras/Rap GTPase-activating protein SynGAP|synaptic Ras GTPase activating protein 1 homolog|synaptic Ras GTPase activating protein, 135kDa|synaptic Ras GTPase-activating protein 1
Swissprots A8MQC4 A2BEL7 Q9UGE2 Q96PV0 Q8TCS2 A2BEL6 A2AB17
Accessions CAA16161 EAX03735 EAX03736 EAX03737 EAX03738 Q96PV0 AK094225 AK124666 AK307888 AL713634 CAD28452 BC148357 AAI48358 BM354009 BX282051 CN412954 DA057307 NM_006772 NP_006763 NM_001130066
Function Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity). {ECO:0000250}.

SynGAP CRISPR/Cas9 KO Plasmid (h) - sc-408793 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP HDR Plasmid (h) - sc-408793-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP Double Nickase Plasmid (h) - sc-408793-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP Double Nickase Plasmid (h2) - sc-408793-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP CRISPR Activation Plasmid (h) - sc-408793-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP CRISPR Activation Plasmid (h2) - sc-408793-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP Lentiviral Activation Particles (h) - sc-408793-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP Lentiviral Activation Particles (h2) - sc-408793-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SynGAP siRNA (h) - sc-42283 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SynGAP shRNA Plasmid (h) - sc-42283-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SynGAP shRNA (h) Lentiviral Particles - sc-42283-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAS p21 RNAi - H00005921-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RAS p21 RNAi - H00005921-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN20893 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20893 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SYNGAP1 siRNA (Human) - CRH5827 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SYNGAP1 - MBS8221365 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SYNGAP1 (NM_006772.2) - SHH421696 from Creative biogene

Category siRNA
Species Reactivities Human

Human SYNGAP1 siRNA - orb266329 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SYNGAP1 shRNA Plasmid (Human) - CHH5827 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SYNGAP1 miRNA 3'UTR clone - MiUTR3H-05917 from Creative biogene

Species Reactivities Human
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