Gene Symbol | CYTH3 |
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Entrez Gene | 9265 |
Alt Symbol | ARNO3, GRP1, PSCD3 |
Species | Human |
Gene Type | protein-coding |
Description | cytohesin 3 |
Other Description | ARF nucleotide-binding site opener 3|PH, SEC7 and coiled-coil domain-containing protein 3|cytohesin-3|general receptor of phosphoinositides 1|pleckstrin homology, Sec7 and coiled-coil domains 3 |
Swissprots | A4D2N8 O43739 |
Accessions | AAS07510 EAL23717 EAW55046 O43739 AJ005197 CAA06434 AJ223957 CAA11686 AK023609 AK295163 BAH11995 AK313728 BAG36470 BC008191 AAH08191 BC028717 AAH28717 BG620295 CB988199 DQ891736 ABM82662 DQ894912 ABM85838 EU176610 ABW03411 NM_004227 NP_004218 |
Function | Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. {ECO:0000269|PubMed:23940353, ECO:0000269|PubMed:9707577}. |
Subcellular Location | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. |
Tissue Specificity | Almost absent from liver, thymus and peripheral blood lymphocytes. |
Top Pathways | Endocytosis |
cytohesin-1 (C-19) - sc-9734 from Santa Cruz Biotechnology
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GRP1 (A-10) - sc-374437 from Santa Cruz Biotechnology
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GRP1 (A-3) - sc-271741 from Santa Cruz Biotechnology
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GRP1 (C-20) - sc-9732 from Santa Cruz Biotechnology
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GRP1 (E-8) - sc-271740 from Santa Cruz Biotechnology
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GRP1 (N-17) - sc-9730 from Santa Cruz Biotechnology
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Anti-Cytohesin 3 antibody - ab155691 from Abcam
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Anti-Cytohesin 3 antibody - ab172351 from Abcam
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Anti-Cytohesin 3 antibody - ab134502 from Abcam
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Anti-Cytohesin 3 antibody - ab56508 from Abcam
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Anti-CYTH3 / GRP1 Antibody (aa371-400, AP) - LS-C255819 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400, APC) - LS-C255818 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400, Biotin) - LS-C255820 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (SEC7 Domain, clone EP394Y) - LS-C49613 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400, FITC) - LS-C255821 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400, Azide-free, HRP) - LS-C255822 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400, PE) - LS-C255823 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (Lys400) - LS-C177289 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa351-400) - LS-C199877 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400) - LS-C167252 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa371-400) - LS-C320726 from LifeSpan Bioscience
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Anti-CYTH3 / GRP1 Antibody (aa1-180, Azide-free) - LS-C327152 from LifeSpan Bioscience
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Cytohesin 3 Antibody - NBP1-90097 from Novus Biologicals
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Cytohesin 3 Antibody (6D3-1A9) - H00009265-M01 from Novus Biologicals
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Cytohesin 3 Antibody - NBP2-16085 from Novus Biologicals
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