Gene Symbol | CYTH3 |
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Entrez Gene | 9265 |
Alt Symbol | ARNO3, GRP1, PSCD3 |
Species | Human |
Gene Type | protein-coding |
Description | cytohesin 3 |
Other Description | ARF nucleotide-binding site opener 3|PH, SEC7 and coiled-coil domain-containing protein 3|cytohesin-3|general receptor of phosphoinositides 1|pleckstrin homology, Sec7 and coiled-coil domains 3 |
Swissprots | A4D2N8 O43739 |
Accessions | AAS07510 EAL23717 EAW55046 O43739 AJ005197 CAA06434 AJ223957 CAA11686 AK023609 AK295163 BAH11995 AK313728 BAG36470 BC008191 AAH08191 BC028717 AAH28717 BG620295 CB988199 DQ891736 ABM82662 DQ894912 ABM85838 EU176610 ABW03411 NM_004227 NP_004218 |
Function | Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. {ECO:0000269|PubMed:23940353, ECO:0000269|PubMed:9707577}. |
Subcellular Location | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Translocates from the cytosol to membranes enriched in phosphatidylinositol 3,4,5-trisphosphate. |
Tissue Specificity | Almost absent from liver, thymus and peripheral blood lymphocytes. |
Top Pathways | Endocytosis |
Human Cytohesin 3 full length protein - ab160404 from Abcam
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Human Cytohesin 3 full length protein - ab160405 from Abcam
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Human Cytohesin 3 full length protein - ab180299 from Abcam
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CYTH3 / GRP1 Antibody Blocking Peptide - LS-E10255 from LifeSpan Bioscience
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Cytohesin 3 Recombinant Protein - H00009265-P02 from Novus Biologicals
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CYTH3-Antibody-C-term-Blocking-Peptide - BP9673b from Abgent, a WuXi AppTec company
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CYTH3 protein (His tag) - 80R-3791 from Fitzgerald
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Cytohesin 3 (1-399, His-tag) - AR51478PU-N from Acris Antibodies
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Cytohesin 3 (1-399, His-tag) - AR51478PU-S from Acris Antibodies
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Cytohesin 3 - H00009265-P01-10 from Acris Antibodies
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Cytohesin 3 - H00009265-P01-25 from Acris Antibodies
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Cytohesin 3 - H00009265-P02 from Acris Antibodies
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Cytohesin 3 - H00009265-P02-10 from Acris Antibodies
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Cytohesin 3 - H00009265-P02-25 from Acris Antibodies
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CYTH3, 1-399aa, Human, His tag, E.coli - 01-P2658 from ARP American Research Products
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CYTH3 fusion protein - Ag10025 from Proteintech Group
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Recombinant Human CYTH3, GST-tagged - CYTH3-11803H from Creative Biomart
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Recombinant Human CYTH3, His-tagged - CYTH3-165H from Creative Biomart
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GRP1 (K400) Peptide - BS2942P from Bioworld Technology
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Recombinant Human Cytohesin-3(CYTH3) - CSB-YP006469HU CSB-EP006469HU CSB-BP006469HU CSB-MP006469HU from Cusabio
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CYTH3, 1-399aa, Human, His tag, E.coli - ATGP2658 from ATGen
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Cytohesin 3 - TP306003 from Acris Antibodies
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Cytohesin 3 Recombinant Protein Antigen - NBP1-90097PEP from Novus Biologicals
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Cytohesin 3 Protein (Recombinant) - abx263417 from Abbexa
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Human CYTH3 protein - orb259866 from Biorbyt
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