Gene Symbol | RASSF7 |
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Entrez Gene | 8045 |
Alt Symbol | C11orf13, HRAS1, HRC1 |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
Other Description | HRAS1-related cluster protein 1|HRAS1-related cluster-1|Ras association (RalGDS/AF-6) domain family 7|ras association domain-containing protein 7 |
Swissprots | G5E9N9 Q3KP42 Q3KP41 Q02833 |
Accessions | EAX02348 EAX02349 EAX02350 EAX02351 Q02833 AL535761 BC106921 AAI06922 BC106922 AAI06923 CA315057 EU446739 ABZ92268 M91083 AAA58667 XM_005253147 XP_005253204 XM_005253148 XP_005253205 XM_005253149 XP_005253206 XM_005253150 XP_005253207 XM_005253151 XP_005253208 XM_006718338 XP_006718401 XM_006725142 XP_006725205 XM_006725143 XP_006725206 XM_006725144 XP_006725207 XM_006725145 XP_006725208 XM_011520388 XP_011518690 XM_011520389 XP_011518691 XM_011546611 XP_011544913 NM_001143993 NP_001137465 NM_001143994 NP_001137466 NM_003475 NP_003466 |
Function | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. {ECO:0000269|PubMed:20629633, ECO:0000269|PubMed:21278800}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20629633}. Note=Colocalizes with gamma-tubulin. |
RASSF7 (C-6) - sc-374431 from Santa Cruz Biotechnology
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RASSF7 (L-14) - sc-132781 from Santa Cruz Biotechnology
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RASSF7 (Q-12) - sc-132782 from Santa Cruz Biotechnology
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Anti-RASSF7 antibody - ab77348 from Abcam
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Anti-RASSF7 antibody - ab83008 from Abcam
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Anti-RASSF7 antibody - ab130548 from Abcam
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Anti-RASSF7 antibody - ab155561 from Abcam
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Anti-RASSF7 Antibody (aa325-354, AP) - LS-C223844 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354, APC) - LS-C223845 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354, Biotin) - LS-C227000 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354, FITC) - LS-C227001 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354, Azide-free, HRP) - LS-C227002 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354, PE) - LS-C227003 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa325-354) - LS-C324545 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa159-208) - LS-C199520 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa152-165) - LS-C55374 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa251-300) - LS-C107492 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa288-337) - LS-C102750 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa161-210) - LS-C31793 from LifeSpan Bioscience
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Anti-RASSF7 Antibody (aa326-354) - LS-C162465 from LifeSpan Bioscience
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RASSF7 Antibody - NB100-93434 from Novus Biologicals
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RASSF7 Antibody - NBP2-15091 from Novus Biologicals
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RASSF7 Polyclonal Antibody - bs-7845R from Bioss
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Anti-RASSF7 antibody produced in rabbit - AV34390 from Sigma-Aldrich
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Anti-RASSF7 antibody produced in rabbit - SAB2104696 from Sigma-Aldrich
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