Gene Symbol | RASSF7 |
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Entrez Gene | 8045 |
Alt Symbol | C11orf13, HRAS1, HRC1 |
Species | Human |
Gene Type | protein-coding |
Description | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
Other Description | HRAS1-related cluster protein 1|HRAS1-related cluster-1|Ras association (RalGDS/AF-6) domain family 7|ras association domain-containing protein 7 |
Swissprots | G5E9N9 Q3KP42 Q3KP41 Q02833 |
Accessions | EAX02348 EAX02349 EAX02350 EAX02351 Q02833 AL535761 BC106921 AAI06922 BC106922 AAI06923 CA315057 EU446739 ABZ92268 M91083 AAA58667 XM_005253147 XP_005253204 XM_005253148 XP_005253205 XM_005253149 XP_005253206 XM_005253150 XP_005253207 XM_005253151 XP_005253208 XM_006718338 XP_006718401 XM_006725142 XP_006725205 XM_006725143 XP_006725206 XM_006725144 XP_006725207 XM_006725145 XP_006725208 XM_011520388 XP_011518690 XM_011520389 XP_011518691 XM_011546611 XP_011544913 NM_001143993 NP_001137465 NM_001143994 NP_001137466 NM_003475 NP_003466 |
Function | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. {ECO:0000269|PubMed:20629633, ECO:0000269|PubMed:21278800}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20629633}. Note=Colocalizes with gamma-tubulin. |
RASSF7 Antibody Blocking Peptide - LS-E4604 from LifeSpan Bioscience
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RASSF7 Antibody Blocking Peptide - LS-E12185 from LifeSpan Bioscience
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RASSF7 Antibody Blocking Peptide - LS-E21266 from LifeSpan Bioscience
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RASSF7 Antibody Blocking Peptide - LS-E26640 from LifeSpan Bioscience
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RASSF7-Antibody-C-term-Blocking-Peptide - BP16958b from Abgent, a WuXi AppTec company
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RASSF7 blocking peptide - GTX88839-PEP from GeneTex
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NRAS protein - 30R-1492 from Fitzgerald
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RASSF7 Peptide - AC21-1476-P from Abcore
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RASSF7 Peptide - 46-274P from ProSci
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RASSF7 fusion protein - Ag17079 from Proteintech Group
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RASSF7 fusion protein - Ag16123 from Proteintech Group
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Recombinant Human RASSF7, His-tagged - RASSF7-2195H from Creative Biomart
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Recombinant V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS) - RPB294Hu01 from Cloud-clone
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RASSF7 (transcript variant 1) - TP312844 from Acris Antibodies
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RASSF7/HRAS1, Peptide - MBS426081 from MyBioSource
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RASSF7 Peptide, Human - M34GP13015H from Creative Peptides
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RASSF7 Recombinant Protein Antigen - NBP2-58860PEP from Novus Biologicals
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