RAB29

Gene Symbol RAB29
Entrez Gene 8934
Alt Symbol RAB7L, RAB7L1
Species Human
Gene Type protein-coding
Description RAB29, member RAS oncogene family
Other Description RAB7, member RAS oncogene family-like 1|rab-7-like protein 1|ras-related protein Rab-29|ras-related protein Rab-7L1
Swissprots B4E1K3 O14966 C9JE77
Accessions EAW91580 EAW91581 O14966 AK223514 BAD97234 AK303879 BAG64815 AK308359 AK311085 AK313000 BAG35836 BC002585 AAH02585 BT019540 AAV38347 BX647960 CF528995 CR542010 CAG46807 D84488 BAA22160 DA284582 DA377295 DC314882 DC365059 DQ891917 ABM82843 DQ896838 ABM87837 EU176654 ABW03455 XM_005245569 XP_005245626 XM_005245570 XP_005245627 XM_005245571 XP_005245628 XM_006711605 XP_006711668 XM_006711606 XP_006711669 XM_011510096 XP_011508398 NM_001135662 NP_001129134 NM_001135663 NP_001129135 NM_001135664 NP_001129136 NM_003929 NP_003920
Function Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269|PubMed:22042847, ECO:0000269|PubMed:24788816}.
Subcellular Location Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Note=Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus. Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus. Colocalizes with TGN46 at the trans-Golgi network (TGN). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery. {ECO:0000250}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:24788816}.

Rab 7L1 (L-13) - sc-138574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 7L1 (L-13): sc-138574. Western blot analysis of Rab 7L1 expression in non-transfected: sc-117752 (A) and mouse Rab 7L1 transfected: sc-122915 (B) 293T whole cell lysates.

Rab 7L1 (D-8) - sc-398274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 7L1 (D-8): sc-398274. Western blot analysis of Rab 7L1 expression in non-transfected: sc-117752 (A) and mouse Rab 7L1 transfected: sc-122915 (B) 293T whole cell lysates.

Rab 7L1 (D-13) - sc-138573 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Rab 7L1 (31-E) - sc-81924 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Rab 7L1 (31-E): sc-81924. Western blot analysis of Rab 7L1 expression in Jurkat whole cell lysate.

Anti-RAB7L1 antibody - ab56443 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
ICC/IF image of ab56443 stained A549 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab56443 at 10µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 goat anti- mouse (ab150117) IgG (H+L) preadsorbed, used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-RAB7L1 antibody - ab101394 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-RAB7L1 antibody (ab101394) at 1/500 dilution + A431 whole cell lysate at 30 µg

Anti-RAB7L1 antibody - ab199644 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RAB7L1 antibody (ab199644) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L(HRP) at 1/5000 dilution

Anti-RAB7L1 antibody - ab137947 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RAB7L1 antibody (ab137947) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-RAB7L1 antibody - ab172314 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RAB7L1 antibody (ab172314) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with RAB7L1Lane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-RAB7L1 antibody - C-terminal - ab135419 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RAB7L1 antibody - C-terminal (ab135419) at 1 µg/ml + Human placenta lysate at 10 µg

Anti-RAB29 / RAB7L1 Antibody (aa97-146) - LS-C200556 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using RAB7L1 antibody.

Anti-RAB29 / RAB7L1 Antibody (aa156-201) - LS-C313905 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB29 / RAB7L1 Antibody (aa104-153) - LS-C152183 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB7L1 antibody Western Blot of Placenta.

Anti-RAB7L1 Antibody (aa1-204, Azide-free) - LS-C328433 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RAB29 / RAB7L1 Antibody (N-Terminus) - LS-C169786 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB29 / RAB7L1 Antibody (aa115-164) - LS-C120315 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HT-29 cells, using RAB7L1 Antibody. The lane on the right is treated with the synthesized peptide.

RAB7L1 Antibody - NBP1-87173 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RAB7L1 Antibody [NBP1-87173] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

RAB7L1 Antibody (2B8) - H00008934-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B8
Western Blot: RAB7L1 Antibody (2B8) [H00008934-M03] - Analysis of RAB7L1 expression in Jurkat (Cat # L017V1).

RAB7L1 Antibody - H00008934-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RAB7L1 Antibody [H00008934-D01P] - Analysis of RAB7L1 expression in mouse liver.

RAB7L1 Antibody - 32520002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ELISA: RAB7L1 Antibody [32520002]

RAB7L1 Antibody - NBP2-20046 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RAB7L1 Antibody [NBP2-20046] - Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE gel, diluted at 1:500.

RAB7L1 Antibody - H00008934-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RAB7L1 Antibody [H00008934-B01P] - Analysis of RAB7L1 expression in transfected 293T cell line by RAB7L1 polyclonal antibody. Lane 1: RAB7L1 transfected lysate(22.33 KDa). Lane 2: Non-transfected lysate.

Anti-RAB7L1 antibody produced in rabbit - HPA026303 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RAB7L1: <B>Cat. No. HPA026303</B>: Immunohistochemical staining of human adrenal gland shows strong cytoplasmic positivity in cortical cells.

Monoclonal Anti-RAB7L1 antibody produced in mouse - WH0008934M3 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B8
<B>Immunoblotting</B><BR/>Monoclonal Anti-RAB7L1, <B>Cat. No. WH0008934M3</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~23.1 kDa using Jurkat lysate.

Anti-RAB7L1 antibody produced in mouse - SAB1406758 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RAB7L1: <B>Cat. No. SAB1406758</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~22.3 kDa using RAB7L1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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