RAB29

Gene Symbol RAB29
Entrez Gene 8934
Alt Symbol RAB7L, RAB7L1
Species Human
Gene Type protein-coding
Description RAB29, member RAS oncogene family
Other Description RAB7, member RAS oncogene family-like 1|rab-7-like protein 1|ras-related protein Rab-29|ras-related protein Rab-7L1
Swissprots B4E1K3 O14966 C9JE77
Accessions EAW91580 EAW91581 O14966 AK223514 BAD97234 AK303879 BAG64815 AK308359 AK311085 AK313000 BAG35836 BC002585 AAH02585 BT019540 AAV38347 BX647960 CF528995 CR542010 CAG46807 D84488 BAA22160 DA284582 DA377295 DC314882 DC365059 DQ891917 ABM82843 DQ896838 ABM87837 EU176654 ABW03455 XM_005245569 XP_005245626 XM_005245570 XP_005245627 XM_005245571 XP_005245628 XM_006711605 XP_006711668 XM_006711606 XP_006711669 XM_011510096 XP_011508398 NM_001135662 NP_001129134 NM_001135663 NP_001129135 NM_001135664 NP_001129136 NM_003929 NP_003920
Function Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269|PubMed:22042847, ECO:0000269|PubMed:24788816}.
Subcellular Location Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Note=Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus. Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus. Colocalizes with TGN46 at the trans-Golgi network (TGN). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery. {ECO:0000250}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:24788816}.

Human RAB7L1 full length protein - ab160266 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160266 on a 12.5% SDS-PAGE stained with Coomassie Blue.

RAB29 / RAB7L1 Antibody Blocking Peptide - LS-E24129 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RAB29 / RAB7L1 Antibody Blocking Peptide - LS-E24128 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human RAB7L1 Protein - H00008934-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

RAB7L1 Blocking Peptide - abx063530 from Abbexa

Category Peptide
Species Human, Mouse, Rat

RAB7L1 - H00008934-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

RAB7L1 - H00008934-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

RAB7L1 fusion protein - ag0332 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli-derived, PGEX-4T
Species Human
RAB7L1 fusion protein ag0332 SDS-PAGE

Recombinant Human RAB7L1, GST-tagged - RAB7L1-2134H from Creative Biomart

Category Protein
Source E.coli
Species Human

RAB7L1 Blocking Peptide - CBP2336 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

RAB7L1 Peptide - BS5879P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Human Ras-related protein Rab-7L1(RAB7L1) - CSB-YP019221HU CSB-EP019221HU CSB-BP019221HU CSB-MP019221HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RAB7L1 (transcript variant 1) - TP300431 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RAB7L1

RAB7L1 (transcript variant 2) - TP327093 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RAB7L1

RAB7L1 Recombinant Protein Antigen - NBP1-87173PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

RAB7L1 Peptide, Human - M34GP12879H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

RAB7L1 peptide - orb218199 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

Ras-related protein Rab-7L1 (RAB7L1), Recombinant Protein - MBS1203661 from MyBioSource

Category Protein
Prices $950.00, $950.00, $1,175.00, $1,175.00, $1,425.00, $1,425.00, $1,885.00, $1,885.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human RAB7L1 Protein, MYC/DDK-tagged - RAB29-213H from Creative Biomart

Category Protein
Source HEK293
Species Human
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