RAB29

Gene Symbol	RAB29
Entrez Gene	8934
Alt Symbol	RAB7L, RAB7L1
Species	Human
Gene Type	protein-coding
Description	RAB29, member RAS oncogene family
Other Description	RAB7, member RAS oncogene family-like 1|rab-7-like protein 1|ras-related protein Rab-29|ras-related protein Rab-7L1
Swissprots	B4E1K3 O14966 C9JE77
Accessions	EAW91580 EAW91581 O14966 AK223514 BAD97234 AK303879 BAG64815 AK308359 AK311085 AK313000 BAG35836 BC002585 AAH02585 BT019540 AAV38347 BX647960 CF528995 CR542010 CAG46807 D84488 BAA22160 DA284582 DA377295 DC314882 DC365059 DQ891917 ABM82843 DQ896838 ABM87837 EU176654 ABW03455 XM_005245569 XP_005245626 XM_005245570 XP_005245627 XM_005245571 XP_005245628 XM_006711605 XP_006711668 XM_006711606 XP_006711669 XM_011510096 XP_011508398 NM_001135662 NP_001129134 NM_001135663 NP_001129135 NM_001135664 NP_001129136 NM_003929 NP_003920
Function	Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269|PubMed:22042847, ECO:0000269|PubMed:24788816}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Note=Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus. Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus. Colocalizes with TGN46 at the trans-Golgi network (TGN). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery. {ECO:0000250}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:24788816}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab 7L1 CRISPR/Cas9 KO Plasmid (h) - sc-403366 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 HDR Plasmid (h) - sc-403366-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 Double Nickase Plasmid (h) - sc-403366-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 Double Nickase Plasmid (h2) - sc-403366-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 CRISPR Activation Plasmid (h) - sc-403366-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 CRISPR Activation Plasmid (h2) - sc-403366-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 Lentiviral Activation Particles (h) - sc-403366-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 Lentiviral Activation Particles (h2) - sc-403366-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rab 7L1 siRNA (h) - sc-88818 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rab 7L1 shRNA Plasmid (h) - sc-88818-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rab 7L1 shRNA (h) Lentiviral Particles - sc-88818-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RAB7L1 RNAi - H00008934-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU025091 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17866 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17866 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10502 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10502

RAB7L1 siRNA (Human) - CRH5908 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RAB7L1 RNAi - H00008934-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

RAB7L1 - MBS8208281 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RAB7L1 (NM_003929.2) - SHH388588 from Creative biogene Category siRNA Species Reactivities Human

Human RAB7L1 siRNA - orb266410 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RAB7L1 shRNA Plasmid (Human) - CHH5908 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RAB7L1 miRNA 3'UTR clone - MiUTR4H-TG12267 from Creative biogene Species Reactivities Human

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