RAB29

Gene Symbol	RAB29
Entrez Gene	8934
Alt Symbol	RAB7L, RAB7L1
Species	Human
Gene Type	protein-coding
Description	RAB29, member RAS oncogene family
Other Description	RAB7, member RAS oncogene family-like 1|rab-7-like protein 1|ras-related protein Rab-29|ras-related protein Rab-7L1
Swissprots	B4E1K3 O14966 C9JE77
Accessions	EAW91580 EAW91581 O14966 AK223514 BAD97234 AK303879 BAG64815 AK308359 AK311085 AK313000 BAG35836 BC002585 AAH02585 BT019540 AAV38347 BX647960 CF528995 CR542010 CAG46807 D84488 BAA22160 DA284582 DA377295 DC314882 DC365059 DQ891917 ABM82843 DQ896838 ABM87837 EU176654 ABW03455 XM_005245569 XP_005245626 XM_005245570 XP_005245627 XM_005245571 XP_005245628 XM_006711605 XP_006711668 XM_006711606 XP_006711669 XM_011510096 XP_011508398 NM_001135662 NP_001129134 NM_001135663 NP_001129135 NM_001135664 NP_001129136 NM_003929 NP_003920
Function	Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269|PubMed:22042847, ECO:0000269|PubMed:24788816}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Note=Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus. Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus. Colocalizes with TGN46 at the trans-Golgi network (TGN). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery. {ECO:0000250}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:24788816}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RAB7L1 293T Cell Transient Overexpression Lysate(Denatured) - H00008934-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

RAB7L1 293 Cell Lysate - 408550 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RAB7L1 Overexpression Lysate (Denatured) - H00008934-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

RAB7L1 Overexpression Lysate (Native) - NBL1-15089 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Rab 7L1 (h): 293T Lysate - sc-175274 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

RAB7L1 Over-expression Lysate Product - GWB-1DBCE1 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

RAB7L1 Overexpression Lysate (Native) - NBP2-09576 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RAB7L1 Overexpression Lysate (Denatured) - H00008934-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human RAB7L1 Knockdown Stable Cell Line - CSC-DC012879 from Creative biogene Category Cell Line Species Human

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