FOXP1

Gene Symbol FOXP1
Entrez Gene 27086
Alt Symbol 12CC4, HSPC215, MFH, QRF1, hFKH1B
Species Human
Gene Type protein-coding
Description forkhead box P1
Other Description fork head-related protein like B|forkhead box protein P1|glutamine-rich factor 1|mac-1-regulated forkhead
Swissprots Q9BSG9 Q9H332 B3KV70 Q8NAN6 G5E9V8 Q9P0R1 Q9H334 Q9H333
Accessions CAH05290 CAH05291 CDI30172 EAW65489 EAW65490 EAW65491 EAW65492 EAW65493 EAW65494 EAW65495 EAW65496 EAW65497 EAW65498 EAW65499 EAW65500 Q9H334 AA380962 AB052767 BAC53800 AF146696 AAG47632 AF151049 AAF36135 AF250920 AAL56661 AF275309 AAK69408 AK026898 AK027264 BAB55005 AK074321 BAB85050 AK074569 BAC11065 AK092383 BAC03875 AK122710 BAG53682 AK297649 BAG60016 BC005055 AAH05055 BC054505 BC054815 AAH54815 BC068481 BC071893 AAH71893 BC080521 AAH80521 BC131720 AAI31721 BC152752 AAI52753 BT006643 AAP35289 BX647682 CR457164 CAG33445 DA518749 DA634017 GD144178 KC551794 KC551795 LK937714 XM_005264735 XP_005264792 XM_005264736 XP_005264793 XM_005264737 XP_005264794 XM_005264742 XP_005264799 XM_006713102 XP_006713165 XM_006713103 XP_006713166 XM_006713104 XP_006713167 XM_011533584 XP_011531886 XM_011533585 XP_011531887 XM_011533586 XP_011531888 XM_011533587 XP_011531889 XM_011533588 XP_011531890 XR_427266 XR_940413 XR_940414 NM_001012505 NP_001012523 NM_001244808 NP_001231737 NM_001244810 NP_001231739 NM_001244812 NP_001231741 NM_001244813 NP_001231742 NM_001244814 NP_001231743 NM_001244815 NP_001231744 NM_001244816 NP_001231745 NM_032682 NP_116071
Function Transcriptional repressor (PubMed:18347093). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity; may promote midbrain identity in embryonic stem cell-derived dopamine neu
Subcellular Location Nucleus {ECO:0000269|PubMed:25027557}.
Tissue Specificity Isoform 8 is specifically expressed in embryonic stem cells. {ECO:0000269|PubMed:21924763}.
Top Pathways MicroRNAs in cancer

FoxP1 (D35D10) XP ® Rabbit mAb - 4402 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D35D10
Western blot analysis of extracts from various cell lines using FoxP1 (D35D10) XP ® Rabbit mAb.

FoxP1 Antibody - 2005 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HBP-ALL cells, HCT-15 cells and mouse thymocytes using FoxP1 Antibody.

FOXP1 (A-2) - sc-398811 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FOXP1 (A-2): sc-398811. Western blot analysis of FOXP1 expression in T-47D whole cell lysate.

FOXP1 (B-4) - sc-398885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FOXP1 (B-4): sc-398885. Western blot analysis of FOXP1 expression in non-transfected: sc-117752 (A) and mouse FOXP1 transfected: sc-120311 (B) 293T whole cell lysates.

FOXP1 (G-9) - sc-376650 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FOXP1 (G-9): sc-376650. Western blot analysis of FOXP1 expression in non-transfected: sc-117752 (A) and mouse FOXP1 transfected: sc-120311 (B) 293T whole cell lysates.

FOXP1 (P-20) - sc-31731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FOXP1 (P-20): sc-31731. Western blot analysis of FOXP1 expression in non-transfected: sc-117752 (A) and mouse FOXP1 transfected: sc-120311 (B) 293T whole cell lysates.

FOXP1 (H-70) - sc-66896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

FOXP2 (K-19) - sc-31736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FOXP1 antibody - ab16645 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab16645 was tested in IHC of formalin fixed sections from mouse (over two weeks of age) brain. Antigen retrieval was in citrate buffer and blocking was in 1% BSA. The primary antibody was incubated at a dilution of 1/200 overnight at 4 degrees celsius. The secondary antibody was a biotin conjugated anti-rabbit IgG.

Anti-FOXP1 antibody - ab93807 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma (left) and mouse hybridoma tumor (right) tissues labelling FOXP1 with ab93807 at 1/1000 (1µg/ml). Detection: DAB.

Anti-FOXP1 antibody - ab57216 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-FOXP1 antibody (ab57216) + immunogenObserved band size : 38 kDa (why is the actual band size different from the predicted?)

Anti-FOXP1 antibody - ab93776 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
1 mg HeLa whole cell lysate was immunoprecipitated with 3 µg/mg ab93776. 20% of the immunoprecipitate was used for Western blotting and ab93776 was used at 1 µg/ml followed by a chemiluminescence exposure of 10 seconds to reveal the protein bands.

Anti-FOXP1 antibody [EPR4113] - ab134055 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4113
All lanes : Anti-FOXP1 antibody [EPR4113] (ab134055) at 1/1000 dilutionLane 1 : Daudi cell lysateLane 2 : MCF7 cell lysateLane 3 : T47D cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-FOXP1 antibody [EPR4113] (Alexa Fluor® 488) - ab197522 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4113
Overlay histogram showing MCF7 cells stained with ab197522 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab197522, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.This antibody gave a positive signal in MCF7 fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-FOXP1 antibody [EPR4113] (Alexa Fluor® 647) - ab196977 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4113
Overlay histogram showing MCF7 cells stained with ab196977 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab196977, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 647 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a solid-state 25mW red diode laser (635 nm) and 675/30 bandpass filter.This antibody gave a positive signal in MCF7 fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-FOXP1 antibody [EPR4113] (HRP) - ab196978 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4113
Anti-FOXP1 antibody [EPR4113] (HRP) (ab196978) at 1/5000 dilution + Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-FOXP1 antibody [EPR4114] - ab134063 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4114
All lanes : Anti-FOXP1 antibody [EPR4114] (ab134063) at 1/1000 dilutionLane 1 : Daudi cell lysateLane 2 : MCF-7 cell lysateLane 3 : T47-D cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-FOXP1 antibody [JC12] - ab32010 from Abcam

Prices $400.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone JC12
All lanes : Anti-FOXP1 antibody [JC12] (ab32010) at 1/500 dilutionLane 1 : BCBL1 human cell lineLane 2 : Mutul human cell line

Anti-FOXP1 antibody - C-terminal - ab191184 from Abcam

Prices $384.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FOXP1 antibody - C-terminal (ab191184) at 1/1000 dilutionLane 1 : A549 cell line lysateLane 2 : Daudi cell line lysateLane 3 : Jurkat cell line lysateLane 4 : MCF7 cell line lysateLane 5 : NCI-N292 cell line lysateLysates/proteins at 35 µg per lane.

Anti-FOXP1 Antibody (clone 3G3) - LS-C338526 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3G3
IHC of paraffin-embedded Human lymphoma tissue using anti-FOXP1 mouse monoclonal antibody. (heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-FOXP1 Antibody (clone 4D2) - LS-C174821 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOXP1.

Anti-FOXP1 Antibody (Internal, clone EPR4113) - LS-C138005 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4113
IHC of paraffin-embedded human tonsil tissue using anti-FOXP1 antibody.

Anti-FOXP1 Antibody (aa648-677, Biotin) - LS-C207043 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP1 Antibody (clone 1G7) - LS-C174822 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOXP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOXP1.

Anti-FOXP1 Antibody (aa648-677, Azide-free, HRP) - LS-C207044 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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