CTU1

Gene Symbol CTU1
Entrez Gene 90353
Alt Symbol ATPBD3, NCS6
Species Human
Gene Type protein-coding
Description cytosolic thiouridylase subunit 1
Other Description ATP binding domain 3|ATP-binding domain-containing protein 3|cancer-associated gene protein|cancer-associated protein|cytoplasmic tRNA 2-thiolation protein 1|cytoplasmic tRNA adenylyltransferase 1|cytosolic thiouridylase subunit 1 homolog
Swissprots Q96GZ7 A8K558 Q7Z7A3
Accessions AAP42277 EAW71984 Q7Z7A3 AK291173 BAF83862 BC009037 AAH09037 BX440723 NM_145232 NP_660275
Function Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03053, ECO:0000269|PubMed:19017811}.
Subcellular Location Cytoplasm.
Top Pathways Sulfur relay system

CTU1 (E-17) - sc-241204 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CTU1 (V-17) - sc-241205 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ATPBD3 antibody - ab185473 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of Human PC3 cells labeling ATPBD3 with ab185473 at 4µg/ml.

Anti-ATPBD3 antibody - ab136083 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ATPBD3 antibody (ab136083) at 1/500 dilution + 293 cell lysate at 30 µg

Anti-CTU1 Antibody (aa215-245, AP) - LS-C233006 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245, PE) - LS-C233011 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245, APC) - LS-C233007 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245, FITC) - LS-C233009 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245, Biotin) - LS-C233008 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245, Azide-free, HRP) - LS-C249493 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa215-245) - LS-C319713 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTU1 Antibody (aa291-340) - LS-C119120 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from LOVO cells, using ATPBD3 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CTU1 Antibody (aa269-318) - LS-C200162 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of the lysates from 293 cells using ATPBD3 antibody.

Anti-CTU1 Antibody (aa215-245) - LS-C156677 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
ATPBD3 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

CTU1 Antibody - NBP1-71550 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CTU1 Antibody [NBP1-71550] - Analysis of extracts from LOVO cells, using CTU1 Antibody. The lane on the right is treated with the synthesized peptide.

ANTI-ATPBD3 (CENTER) antibody produced in rabbit - SAB1303372 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>ATPBD3 (Center): <B>Cat. No. SAB1303372</B>: ATPBD3 in Human pancreas tissue with ATPBD3 antibody (Center) at 12.5 μg/mL.

Anti-ATPBD3, C-Terminal antibody produced in rabbit - SAB4503533 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATPBD3, C-Terminal: <B>Cat. No. SAB4503533</B>: Immunoblotting analysis of extracts from LOVO cells, using Anti-ATPBD3, C-Terminal antibody. The lane on the left was treated with the Anti-ATPBD3, C-Terminal antibody. The lane on the right (negative control) was treated with both Anti-ATPBD3, C-Terminal antibody and the synthesized immunogen peptide.

Anti-CTU1 antibody produced in rabbit - HPA053797 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CTU1: <B>Cat. No. HPA053797</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

CTU1 Antibody - C-terminal region (ARP67471_P050) - ARP67471_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTU1 Antibody - middle region (OAAB00356) - OAAB00356 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ATPBD3-Antibody-Center - AP10349c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ATPBD3 Antibody (Center) (Cat. #AP10349c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ATPBD3 antibody detected the ATPBD3 protein (arrow).
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