CTU1

Gene Symbol CTU1
Entrez Gene 90353
Alt Symbol ATPBD3, NCS6
Species Human
Gene Type protein-coding
Description cytosolic thiouridylase subunit 1
Other Description ATP binding domain 3|ATP-binding domain-containing protein 3|cancer-associated gene protein|cancer-associated protein|cytoplasmic tRNA 2-thiolation protein 1|cytoplasmic tRNA adenylyltransferase 1|cytosolic thiouridylase subunit 1 homolog
Swissprots Q96GZ7 A8K558 Q7Z7A3
Accessions AAP42277 EAW71984 Q7Z7A3 AK291173 BAF83862 BC009037 AAH09037 BX440723 NM_145232 NP_660275
Function Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03053, ECO:0000269|PubMed:19017811}.
Subcellular Location Cytoplasm.
Top Pathways Sulfur relay system

CTU1 CRISPR/Cas9 KO Plasmid (h) - sc-413839 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 HDR Plasmid (h) - sc-413839-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 Double Nickase Plasmid (h) - sc-413839-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 Double Nickase Plasmid (h2) - sc-413839-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 CRISPR Activation Plasmid (h) - sc-413839-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 CRISPR Activation Plasmid (h2) - sc-413839-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 Lentiviral Activation Particles (h) - sc-413839-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 Lentiviral Activation Particles (h2) - sc-413839-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CTU1 siRNA (h) - sc-97487 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CTU1 shRNA Plasmid (h) - sc-97487-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CTU1 shRNA (h) Lentiviral Particles - sc-97487-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6764 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6764 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CTU1 siRNA (Human) - CRJ3934 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTU1 - MBS8214211 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CTU1 (NM_145232.3) - SHH271733 from Creative biogene

Category siRNA
Species Reactivities Human

Human CTU1 siRNA - orb274435 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTU1 shRNA Plasmid (Human) - CHJ3934 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CTU1 miRNA 3'UTR clone - MiUTR3H-12552 from Creative biogene

Species Reactivities Human
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