CTU1

Gene Symbol CTU1
Entrez Gene 90353
Alt Symbol ATPBD3, NCS6
Species Human
Gene Type protein-coding
Description cytosolic thiouridylase subunit 1
Other Description ATP binding domain 3|ATP-binding domain-containing protein 3|cancer-associated gene protein|cancer-associated protein|cytoplasmic tRNA 2-thiolation protein 1|cytoplasmic tRNA adenylyltransferase 1|cytosolic thiouridylase subunit 1 homolog
Swissprots Q96GZ7 A8K558 Q7Z7A3
Accessions AAP42277 EAW71984 Q7Z7A3 AK291173 BAF83862 BC009037 AAH09037 BX440723 NM_145232 NP_660275
Function Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03053, ECO:0000269|PubMed:19017811}.
Subcellular Location Cytoplasm.
Top Pathways Sulfur relay system

CTU1 overexpression lysate - LY407969 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CTU1 Overexpression Lysate (Native) - NBP2-05488 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CTU1 Overexpression Lysate (Adult Normal) [NBP2-05488] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CTU1.

Panoply™ Human CTU1 Knockdown Stable Cell Line - CSC-DC003831 from Creative biogene

Category Cell Line
Species Human
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