Gene Symbol | SLC17A3 |
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Entrez Gene | 10786 |
Alt Symbol | NPT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 17 (organic anion transporter), member 3 |
Other Description | Na(+)/PI cotransporter 4|sodium-dependent phosphate transport protein 4|sodium/phosphate cotransporter 4|solute carrier family 17 (sodium phosphate), member 3 |
Swissprots | Q8WWC7 O00476 B7Z511 Q9H533 B7WNJ5 |
Accessions | EAW55495 EAW55496 EAW55497 O00476 AK296070 BAH12250 AK296082 BAH12253 AK298271 BAH12747 AK298297 BAH12751 AK298367 BAH12767 BC017952 AAH17952 BX107915 CB163247 DC340735 DC361549 DQ891991 ABM82917 DQ895181 ABM86107 U90545 AAB53423 Z83953 NM_001098486 NP_001091956 NM_006632 NP_006623 |
Function | Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport. |
Subcellular Location | Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in the liver and kidney. It is detected in proximal tubules in renal cortex as well as some tubules and glomeruli, with highest expression at the apical side of proximal tubules (at protein level). {ECO:0000269|PubMed:20810651, ECO:0000269|PubMed:9149941}. |
Human SLC17A3 full length protein - ab161154 from Abcam
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SLC17A3 Antibody Blocking Peptide - LS-E15564 from LifeSpan Bioscience
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Recombinant Human SLC17A3 Protein - H00010786-P01 from Novus Biologicals
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SLC17A3-Antibody-C-term-Blocking-Peptide - BP17839b from Abgent, a WuXi AppTec company
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SLC17A3 Blocking Peptide - 33R-3125 from Fitzgerald
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SLC17A3 / NPT4 - H00010786-P01-10 from Acris Antibodies
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SLC17A3 / NPT4 - H00010786-P01-25 from Acris Antibodies
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SLC17A3 fusion protein - ag9526 from Proteintech Group
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SLC17A3 fusion protein - Ag9708 from Proteintech Group
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Recombinant Human SLC17A3, GST-tagged - SLC17A3-2701H from Creative Biomart
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SLC17A3 Peptide, Human - M34GP14351H from Creative Peptides
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SLC17A3 Recombinant Protein Antigen - NBP1-82535PEP from Novus Biologicals
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Sodium-dependent phosphate transport protein 4 (SLC17A3), Recombinant Protein - MBS1068849 from MyBioSource
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