Gene Symbol | SLC17A3 |
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Entrez Gene | 10786 |
Alt Symbol | NPT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 17 (organic anion transporter), member 3 |
Other Description | Na(+)/PI cotransporter 4|sodium-dependent phosphate transport protein 4|sodium/phosphate cotransporter 4|solute carrier family 17 (sodium phosphate), member 3 |
Swissprots | Q8WWC7 O00476 B7Z511 Q9H533 B7WNJ5 |
Accessions | EAW55495 EAW55496 EAW55497 O00476 AK296070 BAH12250 AK296082 BAH12253 AK298271 BAH12747 AK298297 BAH12751 AK298367 BAH12767 BC017952 AAH17952 BX107915 CB163247 DC340735 DC361549 DQ891991 ABM82917 DQ895181 ABM86107 U90545 AAB53423 Z83953 NM_001098486 NP_001091956 NM_006632 NP_006623 |
Function | Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport. |
Subcellular Location | Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in the liver and kidney. It is detected in proximal tubules in renal cortex as well as some tubules and glomeruli, with highest expression at the apical side of proximal tubules (at protein level). {ECO:0000269|PubMed:20810651, ECO:0000269|PubMed:9149941}. |
SLC17A3 (N-19) - sc-55772 from Santa Cruz Biotechnology
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SLC17A3 (H-53) - sc-367397 from Santa Cruz Biotechnology
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SLC17A3 (S-15) - sc-55773 from Santa Cruz Biotechnology
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Anti-SLC17A3 antibody - ab23332 from Abcam
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Anti-SLC17A3 antibody - ab168662 from Abcam
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Anti-SLC17A3 Antibody (aa171-220) - LS-C40377 from LifeSpan Bioscience
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SLC17A3 Antibody - NBP1-82535 from Novus Biologicals
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SLC17A3 Antibody - NBP1-60014 from Novus Biologicals
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SLC17A3 Antibody - H00010786-B01 from Novus Biologicals
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SLC17A3 Antibody - H00010786-B01P from Novus Biologicals
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Anti-SLC17A3 antibody produced in rabbit - AV42305 from Sigma-Aldrich
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Anti-SLC17A3 antibody produced in mouse - SAB1407052 from Sigma-Aldrich
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SLC17A3 antibody - middle region (ARP42305_P050) - ARP42305_P050 from Aviva Systems Biology
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SLC17A3 antibody - 70R-6935 from Fitzgerald
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SLC17A3 / NPT4 antibody - H00010786-B01 from Acris Antibodies
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SLC17A3 / NPT4 antibody - H00010786-B01P from Acris Antibodies
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SLC17A3 Antibody - 29-731 from ProSci
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SLC17A3 antibody - 16404-1-AP from Proteintech Group
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SLC17A3 Antibody - GWB-BBBE40 from Genway Biotech
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Anti-SLC17A3 (full length) polyclonal antibody - DPABH-07360 from Creative Diagnostics
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Anti-SLC17A3 monoclonal antibody - DCABH-16857 from Creative Diagnostics
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SLC17A3 Polyclonal Antibody - PA1-24430 from Thermo Fisher Scientific
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SLC17A3, Polyclonal Antibody - MBS647246 from MyBioSource
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SLC17A3-antibody-middle-region-AI11996 - AI11996 from Abgent, a WuXi AppTec company
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SLC17A3, Polyclonal Antibody - MBS5303009 from MyBioSource
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