TLR5

Gene Symbol	TLR5
Entrez Gene	7100
Alt Symbol	MELIOS, SLE1, SLEB1, TIL3
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 5
Other Description	systemic lupus erythematosus susceptibility 1|toll/interleukin-1 receptor-like protein 3
Swissprots	O60602 D3DTB8 Q32MI3 B1AZ05 B9VJ63 B3Y633 D1CS80 O15456 Q32MI2
Accessions	AAZ17462 AAZ17463 AAZ17464 AAZ17465 AAZ17466 AAZ17467 AAZ17468 AAZ17469 AAZ17470 AAZ17471 AAZ17472 AAZ17473 ACM69017 ACM69018 ACM69019 ACM69020 ACM69021 ACM69022 ACM69023 ACM69024 ACM69025 ACM69026 ACM69027 ACM69028 ACM69029 ACM69030 ACM69031 ACM69032 ACM69033 ACM69034 EAW93262 EAW93263 O60602 AB060695 BAB43955 AB445645 BAG55042 AF051151 AAC34376 AI628024 BC109118 AAI09119 BC109119 AAI09120 BQ025528 DB448079 U88881 AAC34136 XM_005273241 XP_005273298 XM_005273242 XP_005273299 XM_005273243 XP_005273300 XM_006711504 XP_006711567 XM_006711505 XP_006711568 XM_006711506 XP_006711569 XM_011509937 XP_011508239 NM_003268 NP_003259
Function	Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:11323673}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
Top Pathways	Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Salmonella infection, Legionellosis, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TLR5 overexpression lysate - LY401126 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

TLR5 293 Cell Lysate - 401047 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

TLR5 Overexpression Lysate (Native) - NBL1-16954 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Human TLR5 Stable Cell Line - NBP2-26269 from Novus Biologicals Category Cell Line Prices $849.00 Sizes 1 vial Species Human

TLR5 Over-expression Lysate Product - GWB-407B54 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Panoply™ Human TLR5 Knockdown Stable Cell Line - CSC-DC016004 from Creative biogene Category Cell Line Species Human

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