TLR5

Gene Symbol	TLR5
Entrez Gene	7100
Alt Symbol	MELIOS, SLE1, SLEB1, TIL3
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 5
Other Description	systemic lupus erythematosus susceptibility 1|toll/interleukin-1 receptor-like protein 3
Swissprots	O60602 D3DTB8 Q32MI3 B1AZ05 B9VJ63 B3Y633 D1CS80 O15456 Q32MI2
Accessions	AAZ17462 AAZ17463 AAZ17464 AAZ17465 AAZ17466 AAZ17467 AAZ17468 AAZ17469 AAZ17470 AAZ17471 AAZ17472 AAZ17473 ACM69017 ACM69018 ACM69019 ACM69020 ACM69021 ACM69022 ACM69023 ACM69024 ACM69025 ACM69026 ACM69027 ACM69028 ACM69029 ACM69030 ACM69031 ACM69032 ACM69033 ACM69034 EAW93262 EAW93263 O60602 AB060695 BAB43955 AB445645 BAG55042 AF051151 AAC34376 AI628024 BC109118 AAI09119 BC109119 AAI09120 BQ025528 DB448079 U88881 AAC34136 XM_005273241 XP_005273298 XM_005273242 XP_005273299 XM_005273243 XP_005273300 XM_006711504 XP_006711567 XM_006711505 XP_006711568 XM_006711506 XP_006711569 XM_011509937 XP_011508239 NM_003268 NP_003259
Function	Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:11323673}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
Top Pathways	Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Salmonella infection, Legionellosis, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TLR5 peptide - ab40018 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human TLR5 protein fragment - ab112363 from Abcam Category Protein Source Wheat germ Species Human

Human TLR5 protein fragment - ab152752 from Abcam Category Protein Source Wheat germ Species Human

TLR5 Antibody Blocking Peptide - LS-E3788 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR5 Antibody Blocking Peptide - LS-E3789 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR5 Antibody Blocking Peptide - LS-E30191 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TLR5 Antibody Blocking Peptide - LS-E30192 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TLR5 Antibody Blocking Peptide - LS-E11088 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR5 Partial Recombinant Protein - H00007100-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TLR5 Protein - H00007100-Q03 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TLR5 Blocking Peptide - NBP1-76661PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TLR5 Blocking Peptide - NBP1-76662PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TLR5 Blocking Peptide - 33R-10801 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TLR5 Blocking Peptide - 33R-7642 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Toll Like Receptor 5 Protein - abx069368 from Abbexa Category Protein Source E.coli Species Human

Human Toll Like Receptor 5 Protein - abx069370 from Abbexa Category Protein Source E.coli Species Human

Human Toll Like Receptor 5 Protein - abx069369 from Abbexa Category Protein Source E.coli Species Human

TLR5 - H00007100-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TLR5 - H00007100-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TLR5 - H00007100-Q03-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TLR5 - H00007100-Q03-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TLR5 Control Peptide - AP10344CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 100 µg

TLR5 Control Peptide - AP30901CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

TLR5 Control Peptide - AP30902CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Toll Like Receptor 5 (TLR5), Human - 20-8241 from ARP American Research Products Category Protein Prices $289.00 Sizes 50 µg Source E.coli Species Human

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