TLR5

Gene Symbol TLR5
Entrez Gene 7100
Alt Symbol MELIOS, SLE1, SLEB1, TIL3
Species Human
Gene Type protein-coding
Description toll-like receptor 5
Other Description systemic lupus erythematosus susceptibility 1|toll/interleukin-1 receptor-like protein 3
Swissprots O60602 D3DTB8 Q32MI3 B1AZ05 B9VJ63 B3Y633 D1CS80 O15456 Q32MI2
Accessions AAZ17462 AAZ17463 AAZ17464 AAZ17465 AAZ17466 AAZ17467 AAZ17468 AAZ17469 AAZ17470 AAZ17471 AAZ17472 AAZ17473 ACM69017 ACM69018 ACM69019 ACM69020 ACM69021 ACM69022 ACM69023 ACM69024 ACM69025 ACM69026 ACM69027 ACM69028 ACM69029 ACM69030 ACM69031 ACM69032 ACM69033 ACM69034 EAW93262 EAW93263 O60602 AB060695 BAB43955 AB445645 BAG55042 AF051151 AAC34376 AI628024 BC109118 AAI09119 BC109119 AAI09120 BQ025528 DB448079 U88881 AAC34136 XM_005273241 XP_005273298 XM_005273242 XP_005273299 XM_005273243 XP_005273300 XM_006711504 XP_006711567 XM_006711505 XP_006711568 XM_006711506 XP_006711569 XM_011509937 XP_011508239 NM_003268 NP_003259
Function Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:11323673}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
Top Pathways Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Salmonella infection, Legionellosis, Inflammatory bowel disease (IBD)

TLR5 (H-127) - sc-10742 from Santa Cruz Biotechnology

TLR5 (H-127): sc-10742. Western blot analysis of TLR-5 expression in THP-1 (A) and NAMALWA (B) whole cell lysates.

TLR5 (C-14) - sc-8696 from Santa Cruz Biotechnology

TLR5 (H-18) - sc-16243 from Santa Cruz Biotechnology

TLR5 (H-18): sc-16243. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing cytoplasmic staining of follicle cells.

TLR5 (M-300) - sc-30003 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TLR5 (M-300): sc-30003. Western blot analysis of TLR5 expression in NAMALWA whole cell lysate.

TLR5 (N-15) - sc-8695 from Santa Cruz Biotechnology

TLR5 (85B152.5) - sc-52963 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

TLR5 (B-24) - sc-130897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TLR1 (B-23): sc-130896. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.

TLR5 (19D759.2) - sc-57461 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-TLR5 antibody - ab62460 from Abcam

Prices $387.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 :  Anti-TLR5 antibody (ab62460) at 0.5 µg/mlLane 2 :  Anti-TLR5 antibody (ab62460) at 1 µg/mlLane 3 :  Anti-TLR5 antibody (ab62460) at 2 µg/mlLane 1 : Rat brain cell lysateLane 2 : Rat brain cell lysateLane 3 : Rat brain cell lysateLysates/proteins at 15 µg per lane.

Anti-TLR5 antibody - ab1654 from Abcam

Prices $379.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry with ab1654 on paraffin section of human spleen

Anti-TLR5 antibody - ab37071 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 :  Anti-TLR5 antibody (ab37071) at 0.5 µg/mlLane 2 :  Anti-TLR5 antibody (ab37071) at 1 µg/mlLane 3 :  Anti-TLR5 antibody (ab37071) at 2 µg/mlLane 1 : THP 1 cell lysateLane 2 : THP 1 cell lysateLane 3 : THP 1 cell lysateLysates/proteins at 15 µg per lane.

Anti-TLR5 antibody - ab115603 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115603, at 5µg/ml, staining TLR5 in Formalin-fixed, Paraffin-embedded Human Lung tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-TLR5 antibody - ab156364 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TLR5 antibody (ab156364) at 1/250 dilutionLane 1 : Liver (Mouse) Tissue LysateLane 2 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-TLR5 antibody - ab89497 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-TLR5 antibody (ab89497) at 5 µg/ml + FHs 173 whole cell lysate at 50 µg

Anti-TLR5 antibody - ab13868 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TLR5 antibody (ab13868) at 2 µg/mlLane 1 : Ramos whole cell lysateLane 2 : Raw whole cell lysateLane 3 : Mouse spleen whole cell lysateLane 4 : Mouse lung whole cell lysateLane 5 : Rat lung whole cell lysate

Anti-TLR5 antibody [19D759.2] - ab13876 from Abcam

Prices $389.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 19D759.2
All lanes : Anti-TLR5 antibody [19D759.2] (ab13876) at 2 µg/mlLane 1 : Ramos cell lysateLane 2 : Raw cell lysate

Anti-TLR5 antibody [85B152.5] - ab13875 from Abcam

Prices $382.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 85B152.5
All lanes : Anti-TLR5 antibody [85B152.5] (ab13875) at 2 µg/mlLane 1 : Ramos cell lysateLane 2 : Raw cell lysate

Anti-TLR5 antibody [85B152.5] (FITC) - ab25929 from Abcam

Prices $382.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 85B152.5

Anti-TLR5 antibody [85B152.5] (Phycoerythrin) - ab45119 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 85B152.5
ab45119 used at 5 µg/106 cells staining ThP1 cells by intracellular FACS analysis. The shaded histogram represents ThP1 cells alone, green represents isoytpe control and pink represents TLR5 antibody.

Anti-TLR5 antibody [EPR10373] - ab168382 from Abcam

Prices $99.00, $379.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10373
All lanes : Anti-TLR5 antibody [EPR10373] (ab168382) at 1/1000 dilutionLane 1 : HT29 cell lysateLane 2 : A549 cell lysateLane 3 : THP1 cell lysateLane 4 :  HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-TLR5 Antibody (Internal) - LS-C10742 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TLR5 Antibody (C-Terminus) - LS-C10743 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TLR5 Antibody (C-Terminus) - LS-C10747 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TLR5 Antibody (aa151-181) - LS-C83963 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-TLR5 Antibody - LS-C126384 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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