TLR5

Gene Symbol TLR5
Entrez Gene 7100
Alt Symbol MELIOS, SLE1, SLEB1, TIL3
Species Human
Gene Type protein-coding
Description toll-like receptor 5
Other Description systemic lupus erythematosus susceptibility 1|toll/interleukin-1 receptor-like protein 3
Swissprots O60602 D3DTB8 Q32MI3 B1AZ05 B9VJ63 B3Y633 D1CS80 O15456 Q32MI2
Accessions AAZ17462 AAZ17463 AAZ17464 AAZ17465 AAZ17466 AAZ17467 AAZ17468 AAZ17469 AAZ17470 AAZ17471 AAZ17472 AAZ17473 ACM69017 ACM69018 ACM69019 ACM69020 ACM69021 ACM69022 ACM69023 ACM69024 ACM69025 ACM69026 ACM69027 ACM69028 ACM69029 ACM69030 ACM69031 ACM69032 ACM69033 ACM69034 EAW93262 EAW93263 O60602 AB060695 BAB43955 AB445645 BAG55042 AF051151 AAC34376 AI628024 BC109118 AAI09119 BC109119 AAI09120 BQ025528 DB448079 U88881 AAC34136 XM_005273241 XP_005273298 XM_005273242 XP_005273299 XM_005273243 XP_005273300 XM_006711504 XP_006711567 XM_006711505 XP_006711568 XM_006711506 XP_006711569 XM_011509937 XP_011508239 NM_003268 NP_003259
Function Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:11323673}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
Top Pathways Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Salmonella infection, Legionellosis, Inflammatory bowel disease (IBD)

TLR5 CRISPR/Cas9 KO Plasmid (h) - sc-401154 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 HDR Plasmid (h) - sc-401154-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 Double Nickase Plasmid (h) - sc-401154-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 Double Nickase Plasmid (h2) - sc-401154-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 CRISPR Activation Plasmid (h) - sc-401154-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 CRISPR Activation Plasmid (h2) - sc-401154-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 Lentiviral Activation Particles (h) - sc-401154-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 Lentiviral Activation Particles (h2) - sc-401154-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TLR5 siRNA (h) - sc-40262 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TLR5 shRNA Plasmid (h) - sc-40262-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TLR5 shRNA (h) Lentiviral Particles - sc-40262-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TLR5 RNAi - H00007100-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU155971 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21402 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21402 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TLR5 siRNA (Human) - CRH4867 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TLR5 - MBS8227892 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TLR5 (NM_003268.5) - SHH427996 from Creative biogene

Category siRNA
Species Reactivities Human

Human TLR5 siRNA - orb265369 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TLR5 shRNA Plasmid (Human) - CHH4867 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TLR5 miRNA 3'UTR clone - MiUTR3H-05573 from Creative biogene

Species Reactivities Human
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