ALKBH4

Gene Symbol ALKBH4
Entrez Gene 54784
Alt Symbol ABH4
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 4 (E. coli)
Other Description alkylated DNA repair protein alkB homolog 4|alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|probable alpha-ketoglutarate-dependent dioxygenase ABH4
Swissprots Q9NXW9 Q53H92 Q9H6A4
Accessions CAK32306 EAW50249 Q9NXW9 AK000020 BAA90888 AK026097 BAB15358 AK222689 BAD96409 BC002820 AAH02820 BC017096 AAH17096 BX353099 CA420615 HQ447345 ADQ31831 XM_005250464 XP_005250521 XM_005250465 XP_005250522 NM_017621 NP_060091
Function Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation. {ECO:0000269|PubMed:21166655, ECO:0000269|PubMed:23673617}.
Subcellular Location Cytoplasm. Nucleus. Midbody. Note=Associates with the contractile ring and midbody.
Tissue Specificity Widely expressed, with highest expression in pancreas, ovary and spleen. {ECO:0000269|PubMed:17979886}.

Human ALKBH4 protein fragment - ab127375 from Abcam

Category Protein
Prices $364.00
Sizes 50 µg
Source E. coli
Species Human

ALKBH4 Antibody Blocking Peptide - LS-E1930 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALKBH4-Antibody-Center-Blocking-peptide - BP12774c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ALKBH4 fusion protein - Ag7764 from Proteintech Group

Category Protein
Source E. coli -derived, PGEX-4T
Species Human

ALKBH4 fusion protein - Ag8041 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human

Recombinant Human ALKBH4, GST-tagged - ALKBH4-9585H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Probable alpha-ketoglutarate-dependent dioxygenase ABH4(ALKBH4) - CSB-YP885759HU CSB-EP885759HU CSB-BP885759HU CSB-MP885759HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

ALKBH4 Protein - abx163645 from Abbexa

Category Protein
Species Human

Probable alpha-ketoglutarate-dependent dioxygenase ABH4 (ALKBH4), Recombinant Protein - MBS1477294 from MyBioSource

Category Protein
Prices $1,055.00, $1,055.00, $1,290.00, $1,290.00, $1,650.00, $1,650.00, $2,115.00, $2,115.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

ALKBH4 Recombinant Protein Antigen - NBP2-14737PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ALKBH4 Peptide, Human - M34GP00514H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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