ALKBH4

Gene Symbol ALKBH4
Entrez Gene 54784
Alt Symbol ABH4
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 4 (E. coli)
Other Description alkylated DNA repair protein alkB homolog 4|alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|probable alpha-ketoglutarate-dependent dioxygenase ABH4
Swissprots Q9NXW9 Q53H92 Q9H6A4
Accessions CAK32306 EAW50249 Q9NXW9 AK000020 BAA90888 AK026097 BAB15358 AK222689 BAD96409 BC002820 AAH02820 BC017096 AAH17096 BX353099 CA420615 HQ447345 ADQ31831 XM_005250464 XP_005250521 XM_005250465 XP_005250522 NM_017621 NP_060091
Function Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation. {ECO:0000269|PubMed:21166655, ECO:0000269|PubMed:23673617}.
Subcellular Location Cytoplasm. Nucleus. Midbody. Note=Associates with the contractile ring and midbody.
Tissue Specificity Widely expressed, with highest expression in pancreas, ovary and spleen. {ECO:0000269|PubMed:17979886}.

ALKBH4 CRISPR/Cas9 KO Plasmid (h) - sc-406350 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 HDR Plasmid (h) - sc-406350-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 Double Nickase Plasmid (h) - sc-406350-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 Double Nickase Plasmid (h2) - sc-406350-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 CRISPR Activation Plasmid (h) - sc-406350-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 CRISPR Activation Plasmid (h2) - sc-406350-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 Lentiviral Activation Particles (h) - sc-406350-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 Lentiviral Activation Particles (h2) - sc-406350-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 siRNA (h) - sc-89850 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALKBH4 shRNA Plasmid (h) - sc-89850-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALKBH4 shRNA (h) Lentiviral Particles - sc-89850-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU018521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3069 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3069 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08401 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08401

ALKBH4 siRNA (Human) - CRJ0214 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALKBH4 - MBS8202175 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALKBH4 CRISPR/Cas9 KO Plasmid (h2) - sc-406350-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALKBH4 HDR Plasmid (h2) - sc-406350-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human ALKBH4 (NM_017621.3) - SHH235246 from Creative biogene

Category siRNA
Species Reactivities Human

Human ALKBH4 siRNA - orb270715 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALKBH4 shRNA Plasmid (Human) - CHJ0214 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ALKBH4 miRNA 3'UTR clone - MiUTR3H-12826 from Creative biogene

Species Reactivities Human
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