Gene Symbol | MESDC2 |
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Entrez Gene | 23184 |
Alt Symbol | BOCA, MESD |
Species | Human |
Gene Type | protein-coding |
Description | mesoderm development candidate 2 |
Other Description | LDLR chaperone MESD|mesoderm development protein|renal carcinoma antigen NY-REN-61 |
Swissprots | B4DW84 Q969U1 Q14696 D3DW96 |
Accessions | CAJ42747 EAW99109 EAW99110 Q14696 AI911839 AK026606 AK301416 BAG62946 AY359110 AAQ89468 BC007867 BC009210 AAH09210 BC012746 AAH12746 BE004295 D42039 BAA07640 DA938708 DB365572 LN608572 LN608574 NM_015154 NP_055969 NR_126327 NR_126328 |
Function | Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. {ECO:0000269|PubMed:15014448, ECO:0000269|PubMed:17488095}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:15014448, ECO:0000269|PubMed:17488095}. |
mesoderm development candidate 2, ELISA Kit - MBS9342131 from MyBioSource
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Custom Human MESDC2 ELISA - ELH-MESDC2-1 from RayBiotech
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Human MESDC2 ELISA Kit - E024192 from Biobool
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Custom Human MESDC2 ELISA Kit - orb384663 from Biorbyt
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anti-MESDC2 antibody - ARG55824 from Arigo Biolaboratories
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Human LDLR chaperone MESD (MESDC2) ELISA Kit - AE33749HU from ARP American Research Products
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