Gene Symbol | MESDC2 |
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Entrez Gene | 23184 |
Alt Symbol | BOCA, MESD |
Species | Human |
Gene Type | protein-coding |
Description | mesoderm development candidate 2 |
Other Description | LDLR chaperone MESD|mesoderm development protein|renal carcinoma antigen NY-REN-61 |
Swissprots | B4DW84 Q969U1 Q14696 D3DW96 |
Accessions | CAJ42747 EAW99109 EAW99110 Q14696 AI911839 AK026606 AK301416 BAG62946 AY359110 AAQ89468 BC007867 BC009210 AAH09210 BC012746 AAH12746 BE004295 D42039 BAA07640 DA938708 DB365572 LN608572 LN608574 NM_015154 NP_055969 NR_126327 NR_126328 |
Function | Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. {ECO:0000269|PubMed:15014448, ECO:0000269|PubMed:17488095}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:15014448, ECO:0000269|PubMed:17488095}. |
MESDC2 293T Cell Transient Overexpression Lysate(Denatured) - H00023184-T01 from Acris Antibodies
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MESDC2 overexpression lysate - LY402437 from Acris Antibodies
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MESDC2 293 Cell Lysate - 402132 from ABBIOTEC
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MESDC2 Overexpression Lysate (Native) - NBL1-13014 from Novus Biologicals
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MESDC2 Over-expression Lysate Product - GWB-5ADB60 from Genway Biotech
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Human MESDC2 / MESD HEK293 Cell Lysate (WB positive control) - 10949-H08HL-300 from Sino Biological
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Human MESDC2 Human Cells Transfected Lysate (positive control) (denatured) - orb173428 from Biorbyt
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MESDC2 Overexpression Lysate (Denatured) - H00023184-T01 from Novus Biologicals
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MESDC2 Overexpression Lysate (Denatured) - H00023184-T02 from Novus Biologicals
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Panoply™ Human MESDC2 Knockdown Stable Cell Line - CSC-DC009411 from Creative biogene
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