MGMT

Gene Symbol	MGMT
Entrez Gene	4255
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	O-6-methylguanine-DNA methyltransferase
Other Description	6-O-methylguanine-DNA methyltransferase|O-6-methylguanine-DNA-alkyltransferase|O6-methylguanine-DNA methyltransferase|methylated-DNA--protein-cysteine methyltransferase|methylguanine-DNA methyltransferase
Swissprots	Q5VY78 P16455
Accessions	AAD13867 AGQ03778 EAW49166 EAW49167 P16455 AK293593 BAG57059 BC000824 AAH00824 BI520029 BT006714 AAP35360 DC387686 DQ890723 ABM81649 DQ893901 ABM84827 KC249995 AGQ03777 M29971 AAA59596 M31767 AAA52317 M60761 AAA59594 X54228 CAA38137 XM_005252682 XP_005252739 XM_006717863 XP_006717926 XM_011539817 XP_011538119 NM_002412 NP_002403
Function	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MGMT full length protein - ab136378 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human MGMT full length protein - ab79251 from Abcam Category Protein Source E. coli Species Human

Human MGMT full length protein - ab185395 from Abcam Category Protein Source E. coli Species Human

Human MGMT peptide - ab89380 from Abcam Category Peptide

Human MGMT peptide - ab89381 from Abcam Category Peptide

MGMT Antibody Blocking Peptide - LS-E2019 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGMT Antibody Blocking Peptide - LS-E2753 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGMT Antibody Blocking Peptide - LS-E8879 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGMT Antibody Blocking Peptide - LS-E15474 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGMT Recombinant Protein - H00004255-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MGMT Partial Recombinant Protein - H00004255-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MGMT Protein - NBC1-18534 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Source E.coli Species Human

MGMT-Antibody-N-term-Blocking-peptide - BP12883a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MGMT-Antibody-N-term-Blocking-peptide - BP13848a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MGMT-Antibody-C-term-Blocking-Peptide - BP7341b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MGMT Protein Lysate (APL10432) - APL10432 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MGMT Protein Lysate (APL10433) - APL10433 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MGMT Protein Lysate (APL11028) - APL11028 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MGMT Protein (OPPA02206) - OPPA02206 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human MGMT O protein - orb245522 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human MGMT protein - orb90181 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli Species Human

Human MGMT protein - orb180342 from Biorbyt Category Protein Prices $306.00, $451.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Cysteine methyltransferase protein - 30R-3179 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

MGMT Blocking Peptide - 33R-10934 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

MGMT Blocking Peptide - 33R-4170 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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