MGMT

Gene Symbol MGMT
Entrez Gene 4255
Alt Symbol -
Species Human
Gene Type protein-coding
Description O-6-methylguanine-DNA methyltransferase
Other Description 6-O-methylguanine-DNA methyltransferase|O-6-methylguanine-DNA-alkyltransferase|O6-methylguanine-DNA methyltransferase|methylated-DNA--protein-cysteine methyltransferase|methylguanine-DNA methyltransferase
Swissprots Q5VY78 P16455
Accessions AAD13867 AGQ03778 EAW49166 EAW49167 P16455 AK293593 BAG57059 BC000824 AAH00824 BI520029 BT006714 AAP35360 DC387686 DQ890723 ABM81649 DQ893901 ABM84827 KC249995 AGQ03777 M29971 AAA59596 M31767 AAA52317 M60761 AAA59594 X54228 CAA38137 XM_005252682 XP_005252739 XM_006717863 XP_006717926 XM_011539817 XP_011538119 NM_002412 NP_002403
Function Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Subcellular Location Nucleus.

MGMT CRISPR/Cas9 KO Plasmid (h) - sc-400720 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT HDR Plasmid (h) - sc-400720-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT Double Nickase Plasmid (h) - sc-400720-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT Double Nickase Plasmid (h2) - sc-400720-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT CRISPR Activation Plasmid (h) - sc-400720-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT CRISPR Activation Plasmid (h2) - sc-400720-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT Lentiviral Activation Particles (h) - sc-400720-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT Lentiviral Activation Particles (h2) - sc-400720-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MGMT siRNA (h) - sc-35927 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MGMT shRNA Plasmid (h) - sc-35927-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MGMT shRNA (h) Lentiviral Particles - sc-35927-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU033391 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13303 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13303 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MGMT siRNA (Human) - CRH2893 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MGMT RNAi - H00004255-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MGMT (NM_002412.3) - SHH341683 from Creative biogene

Category siRNA
Species Reactivities Human

MGMT shRNA Plasmid (Human) - CHH2893 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MGMT miRNA 3'UTR clone - MiUTR3H-01420 from Creative biogene

Species Reactivities Human
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